Clinical Trials

RECRUITING
Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Lupus (SIRIUS-SLE 1)
The trial will assess efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Burbank, California, United States
📍 La Jolla, California, United States
📍 Los Angeles, California, United States
📍 Simi Valley, California, United States
122 more locations available...
RECRUITING
Intervention to Improve Communication and Medication Adherence in Lupus
CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). ...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Durham, North Carolina, United States
RECRUITING
A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Lupus
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Lupus in adult patients with moderate to severe symptoms. The main qu...
Conditions:
Lupus Erythematosus, Systemic
Locations:
📍 Fullerton, California, United States
📍 Aurora, Colorado, United States
📍 Boca Raton, Florida, United States
📍 Clearwater, Florida, United States
114 more locations available...
RECRUITING
Cutaneous Lupus Registry
Approximately 1.4 million individuals in the United States have systemic lupus erythematosus, and about 85% of these individuals develop skin lesions ...
Conditions:
Lupus Erythematosus
Locations:
📍 Dallas, Texas, United States
NOT_YET_RECRUITING
A 2-stage, Phase III Study on the Effectiveness and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
This study aims to assess the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult patients with cutaneous lupus erythematosus...
Conditions:
Cutaneous Lupus Erythematosus
Locations:
📍 Glendale, Arizona, United States
📍 Phoenix, Arizona, United States
📍 La Jolla, California, United States
📍 Orange, California, United States
108 more locations available...
RECRUITING
Lupus Education Alliance Program
The purpose of this study is to assess the assess the effect of education-only vs. navigation interventions on COVID-19 testing and vaccination for pe...
Conditions:
Systemic Lupus Erythematosus COVID-19
Locations:
📍 New Orleans, Louisiana, United States
RECRUITING
Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Patients With Moderate to Severe Lupus
Lupus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will assess how safe and effective upadac...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Chandler, Arizona, United States
📍 Flagstaff, Arizona, United States
📍 Gilbert, Arizona, United States
📍 Glendale, Arizona, United States
263 more locations available...
RECRUITING
An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney Diseases
The goal of this clinical study is to assess multiple dose levels of povetacicept (ALPN-303) in adults with immunoglobulin A (IgA) nephropathy, membra...
Conditions:
Lupus Nephritis Immunoglobulin A Nephropathy Membranous Nephropathy Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Locations:
📍 Phoenix, Arizona, United States
📍 Phoenix, Arizona, United States
📍 Tucson, Arizona, United States
📍 Valencia, California, United States
24 more locations available...
RECRUITING
A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Patients With Active Lupus
The purpose of this study is to assess the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Lupus (SL...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 La Jolla, California, United States
📍 San Leandro, California, United States
📍 Santa Monica, California, United States
📍 Clearwater, Florida, United States
184 more locations available...
RECRUITING
Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
Hydroxychloroquine (HCQ) is a systemic lupus erythematosus (SLE) medication that has been very effective in reducing lupus disease activity and keepin...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Los Angeles, California, United States
📍 Hackensack, New Jersey, United States
📍 Bronx, New York, United States
📍 New York, New York, United States
6 more locations available...
RECRUITING
FT819 in Moderate to Severe Active Lupus
This is a phase 1 study designed to assess the safety, pharmacokinetics (PK), and anti-B-cell activity of FT819 following treatment with or without au...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Minneapolis, Minnesota, United States
📍 Omaha, Nebraska, United States
NOT_YET_RECRUITING
Long-Term Voclosporin Treatment in Adolescent Subjects With Lupus Nephritis
The purpose of this study is to assess the long-term safety and tolerability of voclosporin for up to an additional 12 months following completion of ...
Conditions:
Adolescent Lupus Nephritis
Locations:
📍 Orlando, Florida, United States
RECRUITING
Engagement in CHildhood-Onset Systemic Lupus
The goal of this observational and pilot study is to better understand how depression symptoms may contribute to how well adolescent and young adults ...
Conditions:
Lupus Erythematosus, Systemic Depression
Locations:
📍 Bronx, New York, United States
RECRUITING
Safety of the Herpes Zoster Subunit Vaccine in Lupus
This randomized, double-blind, placebo-controlled, non-inferiority crossover study will assess the Herpes Zoster Sunbit (HZ/su) vaccine in SLE patient...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 New York, New York, United States
📍 Oklahoma City, Oklahoma, United States
RECRUITING
Relationship Between Data Obtained With the LuGENE® Multiparameter Transcriptomics Blood Test and Clinical and Standard Laboratory Features of Patients With SLE (ReLATE)
This is an open label study to determine the association of the data obtained with LuGENE®, a transcriptomic-based LDT, with standard evaluation of p...
Conditions:
Lupus Erythematosus, Systemic
Locations:
📍 Phoenix, Arizona, United States
📍 Los Angeles, California, United States
📍 Santa Monica, California, United States
📍 New Haven, Connecticut, United States
7 more locations available...

Total Trials: 76 - 90 of 110