Clinical Trials

RECRUITING
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Patients With Lupus (SIRIUS-SLE Extension).
The purpose of this study is to assess long-term safety and tolerability of ianalumab in patients with systemic lupus erythematosus who have previousl...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Clearwater, Florida, United States
📍 Barcelona, Catalunya, Spain
📍 Santiago De Compostela, Galicia, Spain
RECRUITING
Daratumumab to Treat Active Lupus Nephritis
The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in patients with active lupu...
Conditions:
Lupus Nephritis
Locations:
📍 Rochester, Minnesota, United States
RECRUITING
VIBRANT: VIB4920 for Active Lupus Nephritis
This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and...
Conditions:
Lupus Nephritis
Locations:
📍 La Jolla, California, United States
📍 Los Angeles, California, United States
📍 Orange, California, United States
📍 San Francisco, California, United States
13 more locations available...
RECRUITING
Lupus in Gullah Health
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies, multiple organ involvement, and diverse...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Charleston, South Carolina, United States
RECRUITING
Voclosporin in Adolescents With Lupus Nephritis
The purpose of this study is to assess the efficacy and safety of voclosporin compared to placebo in achieving renal response following 24 weeks of th...
Conditions:
Adolescent Lupus Nephritis
Locations:
📍 Chapel Hill, North Carolina, United States
RECRUITING
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Lupus (SIRIUS-SLE 2)
The trial will assess efficacy, safety and tolerability of ianalumab compared to placebo, given as monthly subcutaneous (s.c.) injection on top of sta...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 Irvine, California, United States
📍 La Palma, California, United States
📍 Miami, Florida, United States
87 more locations available...
RECRUITING
Study on DS-7011a in Patients With Lupus
Systemic lupus erythematosus (SLE) is a systemic chronic autoimmune disease characterized by autoantibody production, inflammation, and tissue damage ...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 North Little Rock, Arkansas, United States
📍 North Miami Beach, Florida, United States
📍 Tamarac, Florida, United States
8 more locations available...
RECRUITING
Study of Edecesertib in Patients With Cutaneous Lupus Erythematosus (CLE)
The goal of this clinical study is to test how edecesertib (formerly known as GS-5718) can be useful in treating Cutaneous Lupus Erythematosus (CLE) i...
Conditions:
Cutaneous Lupus Erythematosus (CLE)
Locations:
📍 Fremont, California, United States
📍 La Jolla, California, United States
📍 Upland, California, United States
📍 Aurora, Colorado, United States
26 more locations available...
RECRUITING
Study on Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)
The purpose of this study is to assess the efficacy and safety of zetomipzomib (30 mg or 60 mg) compared with placebo in achieving renal response afte...
Conditions:
Lupus Nephritis
Locations:
📍 Huntsville, Alabama, United States
📍 Surprise, Arizona, United States
📍 Los Alamitos, California, United States
📍 Torrance, California, United States
158 more locations available...
RECRUITING
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA...
Conditions:
Lupus Nephritis
Locations:
📍 Chicago, Illinois, United States
📍 Hackensack, New Jersey, United States
📍 New York, New York, United States
📍 New York, New York, United States
3 more locations available...
RECRUITING
A Study on the Safety, Tolerance, Drug Levels and Drug Effects of BMS-986326 in Adult Patients With Different Forms of Lupus
The purpose of this study is to assess safety, drug levels and drug effects on cells and organs of the body, after receiving multiple increasing doses...
Conditions:
Lupus
Locations:
📍 San Diego, California, United States
📍 Clearwater, Florida, United States
📍 Tampa, Florida, United States
📍 Lawrenceville, Georgia, United States
17 more locations available...
RECRUITING
Study on CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Patients With Severe, Refractory Autoimmune Diseases
The purpose of this study is to establish the tolerability, preliminary efficacy, and pharmacokinetics of CC-97540 in patients with severe, refractory...
Conditions:
Systemic Lupus Erythematosus Idiopathic Inflammatory Myopathy Systemic Sclerosis
Locations:
📍 Aurora, Colorado, United States
📍 Denver, Colorado, United States
📍 New Haven, Connecticut, United States
📍 Jacksonville, Florida, United States
50 more locations available...
RECRUITING
Study on IMPT-514 in Active Refractory Lupus (SLE)
This is a Phase 1/2, multi-center, open-label study evaluating the safety and efficacy of IMPT-514, a bispecific chimeric antigen receptor (CAR) targe...
Conditions:
Systemic Lupus Erythematosus Lupus Nephritis
Locations:
📍 Los Angeles, California, United States
📍 San Francisco, California, United States
📍 Iowa City, Iowa, United States
📍 Detroit, Michigan, United States
2 more locations available...
RECRUITING
Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Lupus
Study Description: Systemic lupus erythematosus (SLE) occurs predominantly in women and is driven by type I interferon dysregulation and neutrophil h...
Conditions:
Systemic Lupus Erythematosus (Sle)
Locations:
📍 Bethesda, Maryland, United States
RECRUITING
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
This multi-site registry, centered at Duke University, will enroll pregnant women with autoimmune and rheumatologic diseases. The main goal of MADRA ...
Conditions:
Autoimmune Diseases Pregnancy Related Systemic Lupus Erythematosus Cutaneous Lupus
3 more conditions available...
Locations:
📍 Durham, North Carolina, United States

Total Trials: 61 - 75 of 110