Clinical Trials

RECRUITING
Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton Therapy
Spatially fractionated radiotherapy (SFRT or GRID) addresses some limitations of traditional stereotactic body radiation therapy by relying on beam co...
Conditions:
Unresectable Solid Tumor Metastatic Cancer
Locations:
📍 Saint Louis, Missouri, United States
RECRUITING
Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
This study is being proposed to evaluate the use of moderate hypofractionated proton therapy in low and intermediate risk prostate cancer patients. Qu...
Conditions:
Prostate Cancer
Locations:
📍 Knoxville, Tennessee, United States
📍 Nashville, Tennessee, United States
RECRUITING
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma
This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiatio...
Conditions:
Recurrent Head and Neck Squamous Cell Carcinoma Recurrent Hypopharyngeal Squamous Cell Carcinoma Recurrent Laryngeal Squamous Cell Carcinoma Recurrent Oral Cavity Squamous Cell Carcinoma
1 more condition available...
Locations:
📍 Birmingham, Alabama, United States
📍 Little Rock, Arkansas, United States
📍 Roseville, California, United States
📍 Roseville, California, United States
135 more locations available...
RECRUITING
The Microbiome, Bile Acids, and Notch in Barrett's Esophagus (BE)
The purpose of this study is to prospectively collect and analyze clinical data and biospecimens from a cohort of 100 patients without BE (20), with n...
Conditions:
Barrett Esophagus Esophageal Adenocarcinoma
Locations:
📍 New York, New York, United States
📍 New York, New York, United States
RECRUITING
Proton RT for the Treatment of Pediatric Rhabdomyosarcoma
The main purpose of this study is to see if using proton beam radiation therapy instead of photon beam radiation therapy can reduce side effects from ...
Conditions:
Rhabdomyosarcoma
Locations:
📍 Boston, Massachusetts, United States
📍 Boston, Massachusetts, United States
📍 Houston, Texas, United States
RECRUITING
Pre-operative Hypofractionated Proton Therapy
This study is being done to examine whether proton therapy for certain kinds of sarcomas (extremity and trunk soft tissue) is safe and effective. As p...
Conditions:
Soft Tissue Sarcoma
Locations:
📍 Washington, District of Columbia, United States
RECRUITING
Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy
This research study is studying Proton Radiation as a possible treatment for brain tumor. The radiation involved in this study is: -Proton Radiation
Conditions:
Brain Tumor
Locations:
📍 Boston, Massachusetts, United States
RECRUITING
Proton Therapy for Esophageal Cancer
The goal of this phase II study is to investigate the feasibility, toxicity and efficacy of a regimen incorporating a proven systemic regimen, carbopl...
Conditions:
Esophagus Cancer
Locations:
📍 Loma Linda, California, United States
RECRUITING
Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy
This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy. The...
Conditions:
Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Head and Neck Carcinoma
Locations:
📍 Knoxville, Tennessee, United States
RECRUITING
Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
Patients with human papillomavirus (HPV)-related oropharyngeal cancer generally have favorable outcomes and how well they do depends on the specific d...
Conditions:
Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Oropharynx Cancer Oropharynx Squamous Cell Carcinoma
1 more condition available...
Locations:
📍 Baltimore, Maryland, United States
📍 Baltimore, Maryland, United States
📍 Bel Air, Maryland, United States
📍 Columbia, Maryland, United States
1 more location available...
RECRUITING
Hypofractionated Accelerated Pelvic Nodal Radiotherapy (GCC 2048)
A phase I trial to determine the safety of delivering three sequentially shorter RT schedules (20, 16, and 12 fractions) of HypoFx pelvic nodal RT in ...
Conditions:
Prostate Cancer Prostate Adenocarcinoma
Locations:
📍 Baltimore, Maryland, United States
RECRUITING
A Trial of Increased Dose Intensity Modulated Proton Therapy (IMPT) for High-Grade Meningiomas
This research study is studying radiation therapy as a possible treatment for meningioma or tumor on the lining of the brain. The study drug or interv...
Conditions:
Meningioma Brain Tumor
Locations:
📍 Boston, Massachusetts, United States
📍 Houston, Texas, United States
RECRUITING
Online Proton Adaptive Radiotherapy
This is a pilot study evaluating the feasibility of daily online adaptive planning for patients undergoing proton radiation therapy. Patients undergo...
Conditions:
Solid Tumor
Locations:
📍 Saint Louis, Missouri, United States
RECRUITING
Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas
The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderl...
Conditions:
Pancreatic Cancer
Locations:
📍 Jacksonville, Florida, United States
📍 Warrenville, Illinois, United States
📍 Flint, Michigan, United States
📍 Fairfax, Virginia, United States
RECRUITING
Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement
This purpose of this study is to examine the placement of proton spots during pencil beam scanning proton therapy for low and intermediate risk prosta...
Conditions:
Prostate Cancer Prostate Adenocarcinoma Prostate Carcinoma
Locations:
📍 Knoxville, Tennessee, United States

Total Trials: 31 - 45 of 82