Clinical Trials

RECRUITING
Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation
The goal of this prospective study to investigate the use of circulating tumor DNA (ctDNA) to guide end of therapy decisions in patients with melanoma...
Conditions:
Melanoma Non-small Cell Lung Cancer
Locations:
📍 Boston, Massachusetts, United States
RECRUITING
Establish ProLung Test Measurement Collection Protocol for Future Studies.
The purpose of this Study is to identify and test different data collection methods to determine which approaches improve the ProLung Testing procedur...
Conditions:
Cancer , Healthy
Locations:
📍 Encinitas, California, United States
📍 Maywood, Illinois, United States
📍 Ogden, Utah, United States
📍 Salt Lake City, Utah, United States
RECRUITING
Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
The subject of this study is the adoptive transfer of selected autologous tumor infiltrating lymphocytes (TIL) after in vitro expansion for the treatm...
Conditions:
HNSCC Melanoma Gynecologic Cancer Colorectal Cancer
2 more conditions available...
Locations:
📍 Portland, Oregon, United States
RECRUITING
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
Study of NGM831 as Monotherapy and in Combination with Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
Conditions:
Pancreatic Cancer Breast Cancer Gastric Cancer Non-small Cell Lung Cancer
12 more conditions available...
Locations:
📍 Gilbert, Arizona, United States
📍 Los Angeles, California, United States
📍 Sarasota, Florida, United States
📍 Tampa, Florida, United States
5 more locations available...
RECRUITING
A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS G12C mutation to determine the maximum tolerated dose and recomm...
Conditions:
Lung Cancer Non Small Cell Lung Cancer Colorectal Cancer Cancer of Pancreas
3 more conditions available...
Locations:
📍 Encinitas, California, United States
📍 Glendale, California, United States
📍 Long Beach, California, United States
📍 Pasadena, California, United States
10 more locations available...
RECRUITING
Molecular Analysis of Oncogenes and Resistance Mechanisms in Lung Cancer
The mechanisms of sensitivity and resistance to oncogene-targeted therapy can be determined from tumor tissue or tumor cell lines derived from availab...
Conditions:
Lung Neoplasms
Locations:
📍 Aurora, Colorado, United States
RECRUITING
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
This trial studies the side effects of radiation therapy followed by atezolizumab in treating patients with stage II or III non-small cell lung cancer...
Conditions:
Recurrent Lung Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage III Lung Cancer AJCC v8 Unresectable Lung Non-Small Cell Carcinoma
Locations:
📍 Birmingham, Alabama, United States
📍 Jonesboro, Arkansas, United States
📍 Sacramento, California, United States
📍 Denver, Colorado, United States
146 more locations available...
RECRUITING
A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer
This is a first-in-human, open label, multicenter study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and the preliminary an...
Conditions:
Solid Tumor Glioblastoma Non-small Cell Lung Cancer Breast Cancer
Locations:
📍 Nashville, Tennessee, United States
📍 Houston, Texas, United States
📍 Villejuif, Cedex, France
NOT_YET_RECRUITING
Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Tumors
This phase II trial compares the safety and effect of temozolomide combined with survivin long peptide vaccine (SurVaxM) to temozolomide alone in pati...
Conditions:
Digestive System Neuroendocrine Neoplasm Lung Neuroendocrine Neoplasm Malignant Solid Neoplasm Pancreatic Neuroendocrine Neoplasm
Locations:
📍 Buffalo, New York, United States
RECRUITING
Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors
This trial will find out whether brentuximab vedotin and pembrolizumab work together to treat different types of cancer. There will be several differe...
Conditions:
Melanoma Non-small Cell Lung Cancer Squamous Cell Carcinoma of the Head and Neck
Locations:
📍 Tucson, Arizona, United States
📍 Springdale, Arkansas, United States
📍 Fresno, California, United States
📍 Los Angeles, California, United States
31 more locations available...
RECRUITING
Study of Trilaciclib and Lurbinectidin
Lung cancer is by far the leading cause of cancer death among both men and women worldwide and the second most common cancer in terms of new cases. Sm...
Conditions:
Lung Cancer Small-cell Lung Cancer
Locations:
📍 Lebanon, New Hampshire, United States
📍 Chapel Hill, North Carolina, United States
RECRUITING
Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations
This is a Phase III, randomized, open-label, multicenter, global study to compare the efficacy and safety of Datopotamab Deruxtecan (Dato-DXd) in comb...
Conditions:
NSCLC
Locations:
📍 Phoenix, Arizona, United States
📍 Tucson, Arizona, United States
📍 Hot Springs National Park, Arkansas, United States
📍 Little Rock, Arkansas, United States
303 more locations available...
RECRUITING
A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer
This study is a randomized, double-blind, multicenter, phase III clinical study to compare the clinical efficacy and safety of Serplulimab + chemother...
Conditions:
Limited-Stage Small Cell Lung Cancer
Locations:
📍 Arcadia, California, United States
📍 Los Alamitos, California, United States
📍 Los Angeles, California, United States
📍 Redlands, California, United States
125 more locations available...
RECRUITING
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 mo...
Conditions:
Non Small Cell Lung Cancer Advanced Solid Tumor Metastatic Melanoma Metastatic Head and Neck Carcinoma
15 more conditions available...
Locations:
📍 Springdale, Arkansas, United States
📍 Davis, California, United States
📍 Downey, California, United States
📍 Duarte, California, United States
33 more locations available...
RECRUITING
Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC
The purpose of this study is to: * Test how well the study medicine Abemaciclib, a CDK4/6 inhibitor, works to shrink lung cancer tumors in the body. ...
Conditions:
Small-cell Lung Cancer Large Cell Neuroendocrine Carcinoma of the Lung Extrapulmonary Small Cell Carcinoma
Locations:
📍 Cleveland, Ohio, United States

Total Trials: 31 - 45 of 985