Description
Inclusion Criteria:
- * Male and female, ages of 18 and 85 years and with a prior ICD implant
- * Diagnosed with ischemic cardiomyopathy: Prior myocardial infarction (pathological Q waves or imaging evidence of regional myocardial akinesis/thinning in the absence of a non-ischemic cause)
- * One of the following VT events (within last 6 months): a) ≥3 episodes of VT treated with anti-tachycardia pacing (ATP) or anti-arrhythmic drugs; b) ≥1 appropriate ICD shocks; c) ≥3 VT episodes within 24 hr; d) sustained VT below detection rate of the ICD documented by EKG/cardiac monitor
- * Patients deemed candidates for RF ablation of VT
- * Able and willing to comply with pre-, post-, and follow-up requirements
- * Willing to sign the informed consent
Exclusion Criteria:
- * Serum creatinine \>1.5 mg/dL, or creatinine clearance \<30 ml/min
- * Left ventricular (LV) ejection fraction ≤10%
- * Mobile LV thrombus on echocardiography
- * Absence of vascular access to the LV
- * Disease process likely to limit survival to \<12 months
- * New York Heart Association class IV heart failure
- * Cardiac surgery within the past 2 months (unless VT was incessant),
- * Acute coronary syndrome in the past 2 months (acute thrombus diagnosed by coronary angiography, or dynamic ST segment changes demonstrated on EKG)
- * Another reversible cause of VT (e.g. electrolyte abnormalities, drug-induced arrhythmia)
- * Severe aortic stenosis or mitral regurgitation with a flail leaflet
- * Pregnancy
- * Unwilling or unable to provide informed consent
- * Covid-19 positive testing within 14 days of randomization procedure
- * Enrolled, or planning to get enrolled, in another research study during his/her participation on the Velvet trial
Ages Eligible for Study:
18 Years to 85 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No