Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment
Project ReLearn is testing the efficacy and cost-effectiveness of an Artificial Intelligence system for optimizing weight loss coaching. Participants are randomized to a 1-year weekly gold standard behavioral weight loss remote (video) group treatment or the AI-optimized treatment, which is made up of a combination of remote group treatment, short video call and automated message. In the AI-optimized condition, the system monitors outcomes (via wireless scale, mobile phone app, and wristworn tracker) and, each week, assigns each participant the treatments they have responding to the best, within certain time constraints.
Conditions:
🦠 Obesity 🦠 Weight Loss
🗓️ Study Start (Actual) 22 March 2022
🗓️ Primary Completion (Estimated) 31 August 2025
✅ Study Completion (Estimated) 31 March 2026
👥 Enrollment (Estimated) 336
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Philadelphia, Pennsylvania, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Individuals must be of overweight or obese BMI (27-50 kg/m)
    • * Individuals must be adults (aged 18-70)
    • * Able and willing to engage in the remote program
    • * Able to engage in physical activity (defined as walking two city blocks without stopping)
    • * Individuals must also provide consent for the research team to contact their personal physician if necessary, to provide clearance or to consult about rapid weight loss
    • * Access and willingness to use an Apple or Android smartphone
    • * Satisfactory completion of all enrollment procedures

    Exclusion Criteria:

    • * Medical condition (e.g., cancer, type I diabetes, psychosis, full-threshold eating disorder) that may pose a risk to the participant during intervention or cause a change in weight
    • * Currently pregnant, breastfeeding, or planning to become pregnant in the next 12 months
    • * Recently began or changed the dosage of medication that can cause significant change in weight
    • * History of bariatric surgery
    • * Weight loss of \> 5% in the previous 3 months
Ages Eligible for Study: 18 Years to 70 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 26 January 2022
  • First Submitted that Met QC Criteria 7 February 2022
  • First Posted 9 February 2022

Study Record Updates

  • Last Update Submitted that Met QC Criteria 18 June 2024
  • Last Update Posted 20 June 2024
  • Last Verified June 2024