Description
Inclusion Criteria:
- * • BMI between 30 kg/m2 and 40 kg/m
- * Weight stability, i.e. no continued weight loss of \>1lb per week for a minimum of 4 weeks prior to enrollment
- * Normal thyroid stimulating hormone (TSH) and prolactin
- * Anti-Mullerian Hormone (AMH) \> 1 ng/ml or \< 8 ng/mL
- * Willingness to postpone conception for the first study cycle
- * Involuntary inability to conceive for at least 6 months
- * No clinical diagnosis of polycystic ovarian syndrome (PCOS)
- * Documentation of ovulation with luteal progesterone \>6 ng/ml or positive ovulation predictor home testing
- * Regular menstrual cycles 25-40 days in length
- * Male partner (or sperm donor) with adequate sperm (\>14 million sperm per ml)
- * Hysterosalpingogram or saline infusion sonography demonstrating at least one patent Fallopian tube and a normal uterine cavity
- * Serum total and free testosterone within the 95% CIearance for women with obesity previously studied in our laboratory.
- * Acceptance of the indwelling catheter and willingness to take part in the study
Exclusion Criteria:
Ages Eligible for Study:
19 Years to 37 Years (ADULT)
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers:
Yes