Description
Inclusion Criteria:
- * age: 50-75y old
- * BMI ≥25 and ≤45 kg/m2
- * a diagnosis of prediabetes AND/OR fasting glucose 100 mg/dL and/or HbA1c 5.7% OR Type 2 Diabetes diet-controlled and/or treated with metformin AND meeting 2 or more of the following metabolic syndrome criteria:
- * diagnosis of hypertension on stable medication regimen
- * blood pressure \>120/\>80 mmHg
- * A diagnosis of dyslipidemia on stable regimen
- * triglycerides 150 mg/dL
- * HDL cholesterol men \<40 mg/dL and women \<50 mg/dL
- * waist circumference men: \>102 cm (\>40 in); women \>88 cm (\>35 in)
- * in possession of a smart phone (iPhone or Android)
- * 70% of days with logging adherence (2 or more log entries/day separated by at least 5h)
- * Sleep duration 6-h, with habitual self-reported wake up time \>5AM and before 11 AM and average self reported bed time \<2AM
- * habitually eat breakfast
- * with weight stability within 5% of screening for the last 3 months
- * English speaking (the App has not yet been translated)
- * must live in the New York City metro area
Exclusion Criteria:
- * sleep disorder, e.g. known obstructive sleep apnea (OSA) on CPAP, severe OSA with apnea-hypopnea index \>30 events/h, significant daytime symptoms of OSA, periodic limb movements of sleep, narcolepsy, current shift work or in last 6-mo, travel more than 1 time zone during intervention; severe insomnia with score 15 on Insomnia Severity Index
- * significant organ system dysfunction/disease: severe pulmonary, kidney or cardiovascular disease; evidence of active illness (e.g., fever)
- * history of seizure disorder
- * previous bariatric surgery or on weight loss medication
- * history of or current significant food intake or psychiatric disorder
- * use of dietary supplements and/or medications known to affect sleep, circadian rhythms or metabolic function
- * smoking tobacco or using illegal or recreational drugs
- * consume excessive alcohol (women: \>14 drinks/wk; men: \>21 drinks/wk)
- * anemia (hemoglobin \<10 g/dl and hematocrit \<30%)
- * have conditions that render individual unable to complete all testing procedures \[e.g., unable to stay overnight or frequent travel across 1 time zones\]
- * extreme early and late chronotypes (\> 2AM bed time and wake up time before 5AM and \> 11AM)
- * severe food allergies
- * unwilling/unable to provide informed consent
Ages Eligible for Study:
50 Years to 75 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No