The Effects of Almond on Facial Skin Collagen and Wrinkles
Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.
Conditions:
🦠 Collagen Degeneration 🦠 Wrinkle 🦠 Pigmentation 🦠 Elastic Skin
🗓️ Study Start (Actual) 4 October 2023
🗓️ Primary Completion (Estimated) 30 September 2024
✅ Study Completion (Estimated) 31 December 2024
👥 Enrollment (Estimated) 60
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Sacramento, California, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Subjects 35 to 70 years of age of all skin types
    • * 50% of the subjects will be postmenopausal women determined as \>1-year loss of menstrual period
    • * 50% of the subjects will be premenopausal women
    • * BMI 18.5 - 35 kg/m2
    • * Individuals with a habitual diet that has been maintained for at least 6 months and to be maintained for the duration of the study
    • * Individuals must maintain their usual skincare products, defined as products that has been used for at least 1 month, for the duration of the study

    Exclusion Criteria:

    • * Those with a nut allergy
    • * Those who are unwilling to discontinue oral collagen supplementation 1 month prior to the start of the study
    • * Individuals who are unwilling to discontinue vitamin E or nut containing supplements 2 weeks prior to and during the intervention.
    • * Individuals who are pregnant or breastfeeding
    • * Change in skincare products during the study
    • * Had a medical or cosmetic procedure such as laser resurfacing or plastic surgery to the face within the last 6 months (include botulinum toxin, dermal fillers, collagen, or other similar cosmetic procedure)
    • * Has an autoimmune photosensitive condition or known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
    • * Those with a skin disease on their face that would affect the assessment of their skin based on the assessment of the investigator.
    • * Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years
Ages Eligible for Study: 35 Years to 70 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 3 October 2023
  • First Submitted that Met QC Criteria 6 October 2023
  • First Posted 10 October 2023

Study Record Updates

  • Last Update Submitted that Met QC Criteria 15 June 2024
  • Last Update Posted 18 June 2024
  • Last Verified June 2024