RECRUITING
I'm interested ...!!
Stimulation-Induced Changes in Fronto-Limbic Network
The purpose of this research is to better understand how emotion processing unfolds in the brain using stereoelectroencephalography (sEEG) and direct brain stimulation. This study will use standard behavioral emotion processing tasks combined with neural recording and direct brain stimulation to assess different aspects of emotion processing. Stimulation pulses during pre and post-test periods will assess the effects of stimulation before and after conditioning, the results of which will be combined with results from the activity of each electrode during the emotion tasks to inform us of the nature of emotion processing in the brain and allow us to devise brain modulation protocols in the future.
Conditions:
🦠 Epilepsy 🦠 Mental Disorders
🗓️ Study Start (Actual) 1 March 2023
🗓️ Primary Completion (Estimated) 28 February 2025
✅ Study Completion (Estimated) 1 June 2025
👥 Enrollment (Estimated) 30
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Birmingham, Alabama, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * 1) implantation of sEEG electrodes for SOC epilepsy surgery evaluation
    • * 2) cognitive ability to perform simple tasks and to understand instructions
    • * 3) implanted electrodes in the amygdala and medial PFC regions
    • * 4) competency to understand and sign a written informed consent.

    Exclusion Criteria:

    • * 1) an inability to complete the task
Ages Eligible for Study: 18 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 20 April 2023
  • First Submitted that Met QC Criteria 2 May 2023
  • First Posted 11 May 2023

Study Record Updates

  • Last Update Submitted that Met QC Criteria 22 September 2023
  • Last Update Posted 26 September 2023
  • Last Verified September 2023
I'm interested ...!!