Sleep and Vascular Health Study
Habitual short sleep duration (\< 7 hours/night) increases the risk of cardiovascular disease (CVD) and all-cause mortality. Yet most adults, especially emerging adults (i.e., 18-25 years) do not achieve the National Sleep Foundation recommendation of 7-9 hours of sleep each night. Additionally, the American Heart Association recently included sleep duration in the "Life's Essential 8". This recent development emphasizes the importance of sleep and the need to advance our understanding of how sleep impacts cardiometabolic health (CMH), particularly in emerging adults, a population whose CVD risk trajectory is malleable. Specifically, emerging adulthood is a critical age window when age-related loss of CMH accelerates. Based on my previous work and others, both self-reported and objective measures of poor sleep (e.g., duration, variability) are linked to early signs of elevated CVD risk in emerging adults, such as microvascular dysfunction and elevated central blood pressure (BP), which precede the development of hypertension.
Conditions:
🦠 Sleep 🦠 Vascular Diseases 🦠 Metabolic Disease
🗓️ Study Start (Actual) 1 August 2023
🗓️ Primary Completion (Estimated) 30 September 2024
✅ Study Completion (Estimated) 5 May 2025
👥 Enrollment (Estimated) 60
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Auburn, Alabama, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * 18 - 25 years old
    • * self-report sleeping less than 7 hours a night on average
    • * free from metabolic disease
    • * free from liver disease
    • * free from pulmonary disease
    • * free from cardiovascular disease

    Exclusion Criteria:

    • * blood pressure higher than 140/80 mmHg
    • * BMI greater than 35 kg/m2
    • * use of blood thinners
    • * history of sleeping disorders
    • * no severe food allergies or eating disorders
Ages Eligible for Study: 18 Years to 25 Years (ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 8 June 2023
  • First Submitted that Met QC Criteria 15 June 2023
  • First Posted 26 June 2023

Study Record Updates

  • Last Update Submitted that Met QC Criteria 25 September 2023
  • Last Update Posted 26 September 2023
  • Last Verified June 2023