Description
Inclusion Criteria:
- * High cervical spinal lesion
- * Age 22-65
- * Able to provide informed consent
- * Able to understand and comply with instructions in English
- * Communicate via speech
- * Surgical clearance
- * Life expectancy greater than 12 months
- * Travel up to 60 miles to study locations up to five days per week
- * Caregiver monitor for surgical site complications and behavioral changes on a daily basis
- * Psychosocial support system
Exclusion Criteria:
- * Presence of memory problems
- * Intellectual impairment
- * Psychotic illness or chronic psychiatric disorder, including major depression if untreated
- * Poor visual acuity
- * Pregnancy
- * Active infection or unexplained fever
- * Scalp lesions or skin breakdown
- * HIV or AIDS infection
- * Active cancer or chemotherapy
- * Diabetes
- * Autonomic dysreflexia
- * History of seizure
- * Implanted hydrocephalus shunt
- * Previous neurosurgical history affecting parietal lobe function
- * Medical conditions contraindicating surgery and chronic implantation of a medical device
- * Prior cranioplasty
- * Unable to undergo MRI or anticipated need for MRI during study
- * Nursing an infant or unwilling to bottle-feed infant
- * Chronic oral or intravenous use of steroids or immunosuppressive therapy
- * Suicidal ideation
- * Drug or alcohol dependence
- * Planning to become pregnant, or unwilling to use adequate birth control
- * Implanted Cardiac Defibrillator, Pacemaker, vagal nerve stimulator, or spinal cord stimulator.
- * Implanted deep brain stimulator (DBS), DBS leads, or cochlear implant.
Ages Eligible for Study:
22 Years to 65 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No