Rowing Following Breast Cancer Chemotherapy
There are more than 3.8 million breast cancer survivors in the United States and cancer survivors have a higher risk of cardiovascular disease (CVD) due to chemotherapy than adults without cancer. Cardiovascular rehabilitation can be an effective strategy to decrease the incidence of CVD and its risk factors in this population. The proposed study may help to examine the effect of a novel exercise intervention on cardiovascular rehabilitation in breast cancer survivors.
Conditions:
🦠 Breast Cancer Survivors
🗓️ Study Start (Actual) 26 February 2024
🗓️ Primary Completion (Estimated) 31 May 2026
✅ Study Completion (Estimated) 31 May 2026
👥 Enrollment (Estimated) 72
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Gainesville, Florida, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * diagnosis of primary invasive non-metastatic breast cancer, stages I-III
    • * female based on biological sex
    • * 40 to 80 years of age
    • * completed breast cancer treatment 6 to 24 months prior to study enrollment. Adjuvant endocrine therapy for breast cancer (e.g., ovarian suppression, SERMs, SERDs, AIs), CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed within 6 months prior to study enrollment and during study participation
    • * absence of contraindications to exercise or study participation
    • * study clinician approval

    Exclusion Criteria:

    • * do not meet inclusion criteria
    • * receiving or scheduled to receive treatment for breast cancer (i.e., chemotherapy, surgery, or radiation) during study participation is not allowed. Adjuvant endocrine therapy, CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed during study participation
    • * lymphedema stage ≥ 2 prior to study enrolment
    • * any relevant cardiovascular diseases (stroke, heart failure, myocardial ischemia during maximal graded exercise test, myocardial infarction, angina pectoris, coronary artery bypass surgery or angioplasty or coronary stent)
    • * current participation in other experimental interventions that may confound interpretation of study findings (e.g., dietary intervention for weight loss)
    • * consistent participation in ≥150 min/week of moderate-intensity rowing exercise training in previous 6 months
Ages Eligible for Study: 40 Years to 80 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 20 March 2023
  • First Submitted that Met QC Criteria 27 April 2023
  • First Posted 8 May 2023

Study Record Updates

  • Last Update Submitted that Met QC Criteria 2 July 2024
  • Last Update Posted 5 July 2024
  • Last Verified July 2024