Rheumatology Patient Registry and Biorepository
To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
Conditions:
🦠 Rheumatic Diseases 🦠 Adult Onset Still Disease 🦠 Ankylosing Spondylitis 🦠 Psoriatic Arthritis 🦠 Reactive Arthritis 🦠 Antiphospholipid Syndrome 🦠 Systemic Lupus Erythematosus 🦠 Behcet Disease 🦠 Dermatomyositis 🦠 Polymyositis 🦠 Giant Cell Arteritis 🦠 Lyme Disease 🦠 Mixed Connective Tissue Disease 🦠 Polymyalgia Rheumatica 🦠 Rheumatoid Arthritis 🦠 Sarcoidosis 🦠 Systemic Sclerosis 🦠 Scleroderma 🦠 Sjogren's Syndrome 🦠 Undifferentiated Connective Tissue Diseases
🗓️ Study Start (Actual) 4 August 2020
🗓️ Primary Completion (Estimated) 1 June 2030
✅ Study Completion (Estimated) 1 June 2030
👥 Enrollment (Estimated) 5000
🔬 Study Type OBSERVATIONAL
📊 Phase N/A
Locations:
📍 New Haven, Connecticut, United States

📋 Eligibility Criteria

Description

  • Inclusion Criteria for Rheumatology Patients:
  • * Patients ≥18 years old with a diagnosis of a rheumatic autoimmune disease including, but not limited to: adult onset Still's disease, ankylosing spondylitis, antiphospholipid syndrome, Behcet's disease, dermatomyositis, giant cell arteritis, mixed connective tissue disease, polymyalgia rheumatica, polymyositis, psoriatic arthritis, reactive arthritis, rheumatoid arthritis, sarcoidosis, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, undifferentiated connective tissue disease and vasculitis.
  • * Receiving clinical care at Yale Rheumatology clinics
  • Exclusion Criteria for Rheumatology Patients:
  • * Unable to provide informed consent
  • * No patients will be excluded based on gender or ethnicity or pregnancy status.
  • * Women who are currently pregnant will need to wait to donate a skin biopsy until after they deliver.
  • * Patients allergic to lidocaine or epinephrine or have a history of impaired wound healing will not be able to donate a skin biopsy.
  • Inclusion Criteria for Healthy Volunteers:
  • * Age ≥ 18 years old
  • * No chronic skin conditions
  • * No diagnosis of a rheumatic autoimmune disease (e.g., lupus, rheumatoid arthritis)
  • * Normal BMI
  • Exclusion Criteria for Healthy Volunteers:
  • * Unable to provide informed consent.
  • * Currently pregnant or nursing unless the study goal is to study pregnant or nursing woman.
  • * Allergies to lidocaine or epinephrine (skin biopsies).
  • * A history of impaired wound healing (skin biopsies).
Ages Eligible for Study: 18 Years to 99 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 20 May 2020
  • First Submitted that Met QC Criteria 20 May 2020
  • First Posted 26 May 2020

Study Record Updates

  • Last Update Submitted that Met QC Criteria 21 December 2023
  • Last Update Posted 2 January 2024
  • Last Verified December 2023