Retinal Vascular Changes During Pregnancy
The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy. Specialized photos of the eye will be taken at three different timepoints: early in pregnancy (first or second trimester), late in pregnancy (third trimester), and after delivery. This imaging is non-invasive and does not require contact with the surface of the eye. The photos taken will allow assessment of specific parameters, like blood flow and the health of specialized cells that support vision. Understanding how the eyes change during pregnancy may help guide how retina specialists understanding of retinal disease during pregnancy and better inform pregnancy outcomes.
Conditions:
🦠 Pregnancy
🗓️ Study Start (Actual) 1 February 2024
🗓️ Primary Completion (Estimated) January 2027
✅ Study Completion (Estimated) January 2027
👥 Enrollment (Estimated) 90
🔬 Study Type OBSERVATIONAL
📊 Phase N/A
Locations:
📍 Nashville, Tennessee, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • 1. Patient age 18 years and older
    • 2. Patient able to provide informed consent
    • 3. Pregnant at time of enrollment and in the 1st or 2nd trimester of pregnancy

    Exclusion Criteria:

    • 1. Other ocular disease that prevents imaging (significant cataract or other media opacity)
    • 2. Unable to comply with imaging or follow-up through duration of study
Ages Eligible for Study: 18 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 2 March 2024
  • First Submitted that Met QC Criteria 7 March 2024
  • First Posted 15 March 2024

Study Record Updates

  • Last Update Submitted that Met QC Criteria 7 March 2024
  • Last Update Posted 15 March 2024
  • Last Verified March 2024