Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors
Exposure to fine particulate matter (PM2.5) air pollution is an established risk factor for cardiovascular (CV) morbidity.
Conditions:
🦠 Cardiometabolic Health
🗓️ Study Start (Actual) 24 February 2020
🗓️ Primary Completion (Estimated) 31 December 2024
✅ Study Completion (Estimated) 1 June 2025
👥 Enrollment (Estimated) 55
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Ann Arbor, Michigan, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Nonsmoker
    • * ≥60 years old
    • * residing in Carpenter Place Apartments

    Exclusion Criteria:

    • * Active cigarette smoker
    • * daily secondhand smoke exposure (self-report)
    • * any CV event (myocardial infarction, stroke, heart failure, revascularization) in the past 3 months
    • * unstable CV condition or risk factor (uncontrolled diabetes, class 3-4 angina or heart failure) or any medical condition that would place the participant at risk from participation or jeopardize study integrity (per investigators)
    • * expected overnight travel outside their apartment during the 14-week study period
    • * unable to provide informed consent
    • * lung disease requiring oxygen
    • * renal dialysis
    • * cancer receiving active treatment or chemotherapy
    • * severe uncontrolled high BP ≥160/100 mm Hg or SBP\<115 mm Hg.
    • * CV medication change in the prior month. If participants are on medications for high BP, diabetes, or a CV condition, they will need to have stable therapy during the prior month with no planned changes during the study period.
Ages Eligible for Study: 60 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 18 September 2019
  • First Submitted that Met QC Criteria 24 September 2019
  • First Posted 25 September 2019

Study Record Updates

  • Last Update Submitted that Met QC Criteria 11 April 2024
  • Last Update Posted 15 April 2024
  • Last Verified April 2024