Rebreathing-induced Hypoxia and Glucose Levels

RECRUITING

I'm interested ...!!

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2 diabetes.

Conditions:

🦠 Hypoxemia

🗓️ Study Start (Actual) 21 October 2021

🗓️ Primary Completion (Estimated) September 2024

✅ Study Completion (Estimated) September 2025

👥 Enrollment (Estimated) 30

🔬 Study Type INTERVENTIONAL

📊 Phase NA

Locations:

📍 Austin, Texas, United States

📋 Eligibility Criteria

Description

Inclusion Criteria:

* Men and women aged 18 to 80 years old

Exclusion Criteria:

* Have uncontrolled stage 2 hypertension (˃140/90 mmHg)
* Are smokers
* Are pregnant
* Have a history of cardiovascular disease or indication of cardiovascular disease such as myocardial infarction, left ventricular hypertrophy, ischemic heart disease (or prior ischemia), stroke, and/or other vascular disease
* Have a history of lung disease
* Are taking insulin or more than one antihypertensive medication
* Have poorly controlled diabetes: HbA1c levels ˃ 9%
* Have been previously diagnosed with diabetic complications (nephropathy, neuropathy, retinopathy) by their family doctor

Ages Eligible for Study: 18 Years to 80 Years (ADULT, OLDER_ADULT)

Sexes Eligible for Study: ALL

Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted 8 May 2022
First Submitted that Met QC Criteria 13 June 2022
First Posted 16 June 2022

Study Record Updates

Last Update Submitted that Met QC Criteria 13 January 2024
Last Update Posted 17 January 2024
Last Verified January 2024