Peripheral Immune System in Individuals With Schizophrenia
The investigators are seeking healthy volunteers and people with schizophrenia or schizoaffective disorder for a clinical study of the immune system in psychotic disorders. This is an observational study, to understand the ways in which the immune system may be contributing to the disease process.
Conditions:
🦠 Schizophrenia 🦠 Schizo Affective Disorder 🦠 Schizophreniform Disorders
🗓️ Study Start (Actual) 1 March 2021
🗓️ Primary Completion (Estimated) 31 December 2024
✅ Study Completion (Estimated) 1 June 2025
👥 Enrollment (Estimated) 100
🔬 Study Type OBSERVATIONAL
📊 Phase N/A
Locations:
📍 Stanford, California, United States

📋 Eligibility Criteria

Description

  • Inclusion Criteria for Subjects with schizophrenia and schizoaffective disorders:
  • * Schizophrenia or schizoaffective disorder diagnosis verified by interview
  • * Diagnosis or initiation of antipsychotic medication was within last 5 years
  • Inclusion Criteria for Healthy Controls:
  • * No known diagnosis of schizophrenia or schizoaffective disorder
  • * No history of depression, anxiety, bipolar disorder, PTSD, agoraphobia, panic disorder, or generalized anxiety disorder
  • * Negative assessment for psychotic symptoms on day of interview
  • Exclusion Criteria (for both groups):
  • * Participants have a history of bleeding disorders or are taking blood thinners.
  • * Participants have a history of epilepsy, known genetic disorders
  • * Immunocompromised state (eg., receiving immunosuppressive therapy, transplant).
  • * History of brain-related disease (eg., stroke)
  • * Any uncontrolled medical disorder such as cancer.
  • * History of substance abuse or positive urine toxicology screen (including test for marijuana) on the day of the blood draw
Ages Eligible for Study: 18 Years to 40 Years (ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 26 October 2021
  • First Submitted that Met QC Criteria 26 October 2021
  • First Posted 5 November 2021

Study Record Updates

  • Last Update Submitted that Met QC Criteria 7 March 2024
  • Last Update Posted 12 March 2024
  • Last Verified March 2024