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Mechanistic Interventions and Neuroscience of Dissociation
The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people. The intervention will be tested in dissociative traumatized people at two sites: Emory University and University of Pittsburgh. The researchers are interested in whether neural networks associated with attentional control and interoceptive awareness can be enhanced in this population. The researchers propose to evaluate whether different body-focused and non-body focused interventions can change these mechanisms.
Conditions:
🦠 Dissociation
🗓️ Study Start (Actual) 18 September 2021
🗓️ Primary Completion (Estimated) 31 January 2026
✅ Study Completion (Estimated) 31 January 2026
👥 Enrollment (Estimated) 200
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Atlanta, Georgia, United States
📍 Pittsburgh, Pennsylvania, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * experience of at least one Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Criterion A trauma (assessed using the Life Events Checklist)
    • * a score of 7 or higher on the Multiscale Dissociation Inventory (MDI) depersonalization subscale
    • * willingness to participate in the study

    Exclusion Criteria:

    • * actively psychotic and cognitively compromised individuals (assessed using the Moderate-severe cognitive impairment screening tool (MoCA) will be excluded
    • * moderate or more severe substance dependence (assessed with the MINI)
    • * persons with imminent risk of physical violence to self or others
Ages Eligible for Study: 18 Years to 65 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 11 December 2020
  • First Submitted that Met QC Criteria 11 December 2020
  • First Posted 17 December 2020

Study Record Updates

  • Last Update Submitted that Met QC Criteria 14 February 2024
  • Last Update Posted 15 February 2024
  • Last Verified February 2024
I'm interested ...!!