Description
- Inclusion Criteria - Cases:
- * Age 50-80 years
- * Subjects who are currently smoking or former smokers, with at least 20 pack-years
- * Subjects with either A high suspicion for lung cancer, with planned biopsy or surgery to establish a definitive diagnosis within 60 days after enrollment or treatment naive lung cancer patients confirmed by pathology.
- Exclusion Criteria - Cases
- * Known diagnosis or treatment of cancer from any kind in the past 5 years, except of fully resected non-melanoma skin cancer or fully-resected carcinoma in situ of the cervix and except from the current lung cancer
- Inclusion Criteria - USPSTF risk
- * Age 50-80 years
- * Subjects who are currently smoking or former smokers, with at least 20 pack-years
- Exclusion Criteria - USPSTF risk
- - Known diagnosis or treatment of cancer of any kind in the past 5 years, except for fully resected non-melanoma skin cancer or fully-resected carcinoma in situ of the cervix
- Inclusion Criteria - Healthy controls
- * Age 20-80 years
- * Never smoker or current / previous smoker \< 20 pack year history
- Exclusion Criteria - Healthy Controls
- * Known diagnosis or treatment of cancer of any kind in the past (lifetime), except for fully resected non-melanoma skin cancer or fully-resected carcinoma in situ of the cervix.
- * Not previously diagnosed with a lung lesion highly suspicious for cancer
- * Under follow up or work up for any lesion suspicious for any type of cancer
- * Presenting with fever with body temperature 100.4°F (38°C) or higher
- * Acute exacerbation or flare of an inflammatory condition requiring escalation in medical therapy within 14 days prior to blood draw
- * Pregnancy
- * Any history of blood product transfusion within 30 days prior to blood draw
Ages Eligible for Study:
20 Years to 80 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Yes