Low Systemic/High Local Exercise Load in Peds SCD
This research study wants to learn about what kind of exercise is best for kids with sickle cell disease. Participating children will have a small amount of blood drawn one time at the beginning of the study. Children will then complete some questionnaires that measure pain, physical function, and emotions (depression, anxiety) and complete some tests that measure physical fitness at the beginning and end of the study. Children will be randomized to either a home-based telehealth (1) walking or (2) strengthening exercise program that lasts for 8-weeks, 3-x week, for 45 minutes each session. Children's participation will last up to 10 weeks.
Conditions:
🦠 Sickle Cell Anemia in Children
🗓️ Study Start (Actual) 19 September 2023
🗓️ Primary Completion (Estimated) 30 June 2025
✅ Study Completion (Estimated) 30 June 2025
👥 Enrollment (Estimated) 60
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Jackson, Mississippi, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * youth 12 to 17 years old
    • * diagnosed with SCD genotype SS, SC, beta-plus thalassemia, or beta-zero thalassemia
    • * has daily access to an Internet enabled device (e.g., smart phone, IPad) A parent (≥21 years old) will also be recruited for each youth participant.

    Exclusion Criteria:

    • * non-English speaking due to lack of available written translation services for informed consent and questionnaires
    • * cognitive impairment (e.g., moderate to profound intellectual disability) that precludes study completion
    • * medical condition (e.g., hypertension, bone fracture) that precludes completing exercise safely (determined by study medical director Dr. McNaull).
Ages Eligible for Study: 12 Years to 17 Years (CHILD)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 8 April 2024
  • First Submitted that Met QC Criteria 23 April 2024
  • First Posted 29 April 2024

Study Record Updates

  • Last Update Submitted that Met QC Criteria 23 April 2024
  • Last Update Posted 29 April 2024
  • Last Verified April 2024