Description
Inclusion Criteria:
- 1. Participation in any of the following parent studies: 2000/0329; 2000/0196; 2004/0205; 2000/0024; 2006/0200; 2006/0508; 2006/0210
- 2. A functioning pancreatic islet graft (absence of graft failure as defined in parent study) requiring immunosuppression.
- 3. Willingness of participants to continue to use an approved method of contraception during and 4 months after study participation.
- 4. Ability to provide written informed consent.
Exclusion Criteria:
- 1. For female subjects: Positive pregnancy test, presently breast-feeding, or unwillingness to use effective contraceptive measures for the duration of the study and 4 months after discontinuation. For male subjects: intent to procreate during the duration of the study or within 4 months after discontinuation or unwillingness to use effective measures of contraception. Oral contraceptives, Norplant®, Depo-Provera®, and barrier devices with spermicide are acceptable contraceptive methods; condoms used alone are not acceptable.
- 2. Any medical condition that, in the opinion of the investigator, will interfere with safe participation in the trial.
Ages Eligible for Study:
18 Years to 65 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No