Is Our Microbiome a Predictor of Cardiac Risk
The purpose of this study is to determine a relationship between a person's flora/bacteria in their gut (the intestinal microbiome) and their risk of cardiovascular disease. Investigators will look at inflammatory markers in the blood and also look at the genome of the bacteria in the gut.
Conditions:
🦠 Coronary Artery Disease
🗓️ Study Start (Actual) November 2013
🗓️ Primary Completion (Estimated) September 2024
✅ Study Completion (Estimated) September 2024
👥 Enrollment (Estimated) 500
🔬 Study Type OBSERVATIONAL
📊 Phase N/A
Locations:
📍 Rochester, Minnesota, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • Anyone undergoing cardiac catheterization for suspected coronary artery disease over age 18.

    Exclusion Criteria:

    • 1. Patients currently on long-term antibiotics who cannot stop them for at least 2 weeks prior to providing a stool sample.
    • 2. Patients on chronic laxatives who cannot stop for at least 2 weeks prior to stool collection.
    • 3. Patients on probiotics and cannot stop for 2 weeks prior to giving a stool sample (yogurt is ok).
    • 4. Patients who are unable to provide a stool sample to Mayo Clinic within 24 hours of collection utilizing Fed Ex overnight mail (i.e. people overseas who are unable to provide a sample before leaving the USA.)
Ages Eligible for Study: 18 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 11 December 2013
  • First Submitted that Met QC Criteria 11 December 2013
  • First Posted 17 December 2013

Study Record Updates

  • Last Update Submitted that Met QC Criteria 24 October 2023
  • Last Update Posted 26 October 2023
  • Last Verified October 2023