Description
Inclusion Criteria:
- - Body mass index 30 - 40 kg/m2
Exclusion Criteria:
- * Not weight stable (\<5% change in body mass over the past six months)
- * Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus)
- * Current, or history of uncontrolled, Stage 2 hypertension (blood pressure \>140 / 90 mmHg; anti-hypertensive medications are permitted)
- * Diagnosed obstructive sleep apnea
- * Previous bariatric surgery
- * Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s)
- * Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping)
- * Pregnant (self-reported and confirmed via urine pregnancy test), lactating (self-reported), or post-menopausal (self-reported) females
- * Prisoners
- * Per the POWERbreatheยฎ company:
- * Patients who have undergone recent abdominal surgery and those with abdominal hernia.
- * Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnea.
- * If a patient is suffering from a ruptured eardrum or any other condition of the ear.
- * Patients with marked elevated left ventricular end-diastolic volume and pressure.
- * Patients with worsening heart failure signs and symptoms after training.
- * If an individual is suffering from a cold, sinusitis or respiratory tract infection, it is advised that they do not use the POWERbreathe device.
Ages Eligible for Study:
20 Years to 45 Years (ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Yes