Impact of Sleep Extension in Adolescents
Many teenagers do not get enough sleep. Obesity and diabetes are increasing in teenagers as well. This study plans to learn more about sleep and insulin resistance (insulin not working) in teenagers, and how these things may be related depending on sleep. This is important to know so that the investigators understand how sleep may play a role in health conditions like extra weight gain (increased food intake and less physical activity) and diabetes. To answer this question, the investigators plan to enroll teenagers who get \<7 hours of sleep on school nights and measure changes in insulin sensitivity and dietary intake after a week of typical sleep (sleeping on their normal school schedule) and a week of longer sleep (spending 1+ hour longer in bed each night).
Conditions:
🦠 Insulin Sensitivity 🦠 Sleep 🦠 Dietary Habits
🗓️ Study Start (Actual) 15 October 2018
🗓️ Primary Completion (Estimated) 31 May 2024
✅ Study Completion (Estimated) 31 August 2024
👥 Enrollment (Estimated) 75
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Aurora, Colorado, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • 1. High school students between the age of 14-19 years
    • 2. have typically insufficient sleep, defined by ≤ 7 hours per night on school days
    • 3. BMI 5th-84th percentile for age and sex
    • 4. habitually sedentary (\< 3 hours of regular physical activity per week)
    • 5. Tanner stage 4 or 5, based on breast development for girls and testicular size for boys.

    Exclusion Criteria:

    • 1. Any medications that affect IR or sleep (e.g., metformin, stimulants, atypical antipsychotics, current use of oral steroids)
    • 2. regular use of melatonin or other sleep aids
    • 3. a prior diagnosis of a sleep disorder (e.g. insomnia, delayed sleep phase syndrome, obstructive sleep apnea)
    • 4. Type 2 diabetes or prediabetes
    • 5. IQ\<70 or severe mental illness that may impact sleep or ability to consent/assent (e.g., schizophrenia, psychotic episodes)
    • 6. teens not enrolled in a traditional high school academic program (e.g., home school students)
    • 7. schedules that would preclude participants from adhering to the sleep manipulation (e.g. night shift employment)
    • 8. travel across more than two time zones in the 2 weeks prior to the study.
Ages Eligible for Study: 14 Years to 19 Years (CHILD, ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 9 April 2018
  • First Submitted that Met QC Criteria 9 April 2018
  • First Posted 18 April 2018

Study Record Updates

  • Last Update Submitted that Met QC Criteria 26 September 2023
  • Last Update Posted 28 September 2023
  • Last Verified September 2023