Immune System Related Kidney Disease

RECRUITING

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Kidney diseases related to the immune system include, nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with connective tissue disorders. This study will allow researchers to admit and follow patients suffering from autoimmune diseases of the kidney. It will attempt to provide information about the causes and specific abnormalities associated with autoimmune kidney disease. Patients with kidney disease as a result of their immune system, and patients with diseases of the immune system who may later develop kidney disease, will be potential subjects for this study. Patients will undergo a history and physical examination, and standard laboratory test to more closely understand the causes, signs, symptoms, and responses to medication of these diseases. Based on these evaluations the patients may qualify as candidates for other experimental studies. At any time these patients may be asked to submit blood or urine samples for further research.

Conditions:

🦠 Kidney Disease 🦠 Nephrotic Syndrome

🗓️ Study Start (Actual) 25 June 1992

🗓️ Primary Completion (Estimated) N/A

✅ Study Completion (Estimated) N/A

👥 Enrollment (Estimated) 2000

🔬 Study Type OBSERVATIONAL

📊 Phase N/A

Locations:

📍 Bethesda, Maryland, United States

📋 Eligibility Criteria

Description

Inclusion Criteria:

In order to be eligible to participate in this study, a participant must meet all of the following criteria:
1. Adults \>= 18 years of age and children 10-17 years of age
2. Participants with
1. known, proven, or suspected immunologically-mediated kidney diseases, including but not limited to nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with other systemic or connective tissue disorders, OR
2. immunologically-mediated diseases with the potential for kidney disease.
3. Ability of the participant or guardian to understand and the willingness of the participant or guardian to provide written informed consent.

Exclusion Criteria:

An individual who meets any of the following criteria will be excluded from participation in this study:
1. Concomitant medical problems which would confound the interpretation of studies of the immunologic kidney disorder.
2. Concomitant medical, surgical, or other conditions for which inadequate facilities or funds are available to support their care at the NIH.

Ages Eligible for Study: 10 Years to N/A (CHILD, ADULT, OLDER_ADULT)

Sexes Eligible for Study: ALL

Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted 20 January 2000
First Submitted that Met QC Criteria 20 January 2000
First Posted 21 January 2000

Study Record Updates

Last Update Submitted that Met QC Criteria 25 July 2024
Last Update Posted 26 July 2024
Last Verified 28 June 2024