Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure Patients
This research study is being done to find out if exercise therapy can help improve the heart function, overall health, and quality of life of patients with pulmonary hypertension caused by heart failure.
Conditions:
🦠 Heart Failure 🦠 Pulmonary Hypertension
🗓️ Study Start (Actual) 1 January 2024
🗓️ Primary Completion (Estimated) August 2025
✅ Study Completion (Estimated) August 2026
👥 Enrollment (Estimated) 40
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Jacksonville, Florida, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * NYHA functional class I-IIIb.
    • * LVEF \< 40%.
    • * Clinically-stable for \> 3 months \[no change in disease status or medication\].
    • * Willing and able to provide written informed consent and perform cycle-ergometer or treadmill based exercise.

    Exclusion Criteria:

    • * NYHA class IV HF.
    • * Diagnosis of diastolic HF.
    • * Comorbidities such as obesity (BMI \>36), uncontrolled systemic hypertension, type 2 diabetes, and COPD (FEV1 \<50%).
    • * Musculoskeletal or other conditions that would limit exercise participation.
    • * Pregnant or nursing women
Ages Eligible for Study: 18 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 26 May 2021
  • First Submitted that Met QC Criteria 26 May 2021
  • First Posted 1 June 2021

Study Record Updates

  • Last Update Submitted that Met QC Criteria 27 March 2024
  • Last Update Posted 28 March 2024
  • Last Verified March 2024