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Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone levels may be associated with an increased risk of dementia. Learning about the association between testosterone levels and risk of dementia may help determine the long-term effects of androgen deprivation therapy and may help improve quality of life.
Conditions:
🦠 Anxiety Disorder 🦠 Depression 🦠 Genetic Disorder 🦠 Hematopoietic and Lymphoid Cell Neoplasm 🦠 Malignant Solid Neoplasm
🗓️ Study Start (Actual) 13 February 2020
🗓️ Primary Completion (Estimated) 30 November 2025
✅ Study Completion (Estimated) 30 November 2025
👥 Enrollment (Estimated) 700000
🔬 Study Type OBSERVATIONAL
📊 Phase N/A
Locations:
📍 Houston, Texas, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Have volunteered to participate in institutional or national biobanks, mainly the UK Biobank and the Kaiser Permanente Research Bank, and those that have previously participated in studies that resulted in de-identified clinical and genetic data being make available on public archives, mainly the database of Genotypes and Phenotypes (dbGaP)
    • * No special populations (adults unable to consent, individuals not yet adults, pregnant women, or prisoners)
Ages Eligible for Study: N/A to N/A (CHILD, ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 3 February 2021
  • First Submitted that Met QC Criteria 3 February 2021
  • First Posted 8 February 2021

Study Record Updates

  • Last Update Submitted that Met QC Criteria 14 February 2024
  • Last Update Posted 15 February 2024
  • Last Verified February 2024
I'm interested ...!!