NOT_YET_RECRUITING
I'm interested ...!!
Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension
Primary aldosteronism (PA) is common but rarely recognized cause of hypertension that carries excess cardiovascular and renal risk and has approved targeted treatments. Despite current clinical guidelines that recommend screening in a defined set of high-risk populations, less than 5% of eligible patients are ever screened for PA. This study aims to evaluate the impact of a computer decision support Best Practice Advisory (BPA) alert on rates of screening for PA in guideline-eligible patients, referral to specialist PA care, and treatment with mineralocorticoid receptor antagonists.
Conditions:
🦠 Primary Aldosteronism 🦠 Resistant Hypertension 🦠 Secondary Hypertension 🦠 Hyperaldosteronism 🦠 Mineralocorticoid Excess 🦠 Hypertension
🗓️ Study Start (Actual) December 2023
🗓️ Primary Completion (Estimated) December 2025
✅ Study Completion (Estimated) June 2026
👥 Enrollment (Estimated) 1600
🔬 Study Type INTERVENTIONAL
📊 Phase NA
Locations:
📍 Boston, Massachusetts, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Adults 18+
    • * Seen by clinician at one of the intervention practices at least once in the prior 2 years
    • * History of Hypertension (ICD Code) PLUS ≥1 of the below:
    • * Outpatient BP \>150/100 on 2 or more occasions
    • * Three or more current antihypertensive medication prescriptions
    • * Potassium level \<3.5mEq/L or potassium supplement prescription in the last 5 years
    • * History of Atrial Fibrillation or Atrial Flutter (ICD Code)

    Exclusion Criteria:

    • * History of Primary Aldosteronism (ICD Code)
    • * Prescription for a Mineralocorticoid Receptor Antagonist (MRA) within the last 3 months
Ages Eligible for Study: 18 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 22 June 2023
  • First Submitted that Met QC Criteria 22 June 2023
  • First Posted 29 June 2023

Study Record Updates

  • Last Update Submitted that Met QC Criteria 1 December 2023
  • Last Update Posted 5 December 2023
  • Last Verified December 2023
I'm interested ...!!