Inclusion Criteria:

• * Healthy male and female subjects who are at least 21 years old and who consent to participate in the study.
• * Participants must be willing to have approximately 15 mL of blood drawn via venipuncture and undergo blood pressure measurement.

Exclusion Criteria:

• * Individuals who are below 21 years of age, pregnant, have major cardiovascular problems or sickle cell disease, incarcerated individuals or are unable to give consent will be excluded.
• * Those whose blood pressure is below normal (i.e., 120/80) and those who have cardiovascular problems and taking organic nitrates and sildenafil-based drugs will also be excluded.