Description
Inclusion Criteria:
- * Ambulatory adult subjects (\> 21 years of age) of either gender of any ethnicity
- * Must have taken PPI (omeprazole or equivalent ≥ 20 mg/day, ≥ three times per week, for at least 2 months)
- * Expected to continue at a similar dosage
- * Stage 1 hypertension (with systolic blood pressure \<140 and diastolic \<90)
- * Controlled diabetes mellitus Type II with HbA1C less than 7%
Exclusion Criteria:
- * End-stage renal failure on dialysis
- * Hypercalcemia,
- * Hypophosphatemia (serum P \< 2.5 mg/dL)
- * Hypertension stage 2 or higher
- * Diabetes Type II with HbA1C ≥ 7%
- * Treatment with adrenocorticosteroids, diuretics, non-steroidal anti-inflammatory agents - - Regular dose of magnesium supplements, bisphosphonate, teriparatide, denosumab or selective estrogen receptor modulators
- * Required to take calcium
- Inclusion/exclusion of other drugs or conditions will be considered on an individual basis.
Ages Eligible for Study:
21 Years to 99 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Yes