Inclusion Criteria:

• * Patient is at least 18 years of age at the time of consent.
• * Patient with a full thickness acute wound(s) of the skin:
• 1. On either the upper or lower extremity (including four-compartment leg fasciotomy), in whom DermaClose and/or DermaClose XL is applied during surgery, OR
• 2. Undergoing a four-compartment leg fasciotomy requiring conventional wound dressing.
• * Patient has signed a written informed consent form (ICF) per 21 Code of Federal Regulations (CFR) Part 50.55(e).

Exclusion Criteria:

• * Patient in whom the product was used off-label (except for patients who have the device on for longer than 14 days)
• * Patient with wound(s) that exhibit any of the following:
• * Ischemic tissue,
• * Infected tissue,
• * Acute burned tissue,
• * Fragile tissue at the edges of the wound(s).
• * Patient, who in surgeon's opinion, does not fit the criteria for this study.