Comparison of Type 2 Diabetes Pharmacotherapy Regimens

RECRUITING

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This study is designed to help patients with type 2 diabetes and their clinicians: (a) identify which glucose lowering medications have the most favorable effects on heart health and other patient-important outcomes, (b) inform the timing of medication initiation, and (c) identify whether medication benefits apply equally to all adults with type 2 diabetes, or may be different based on age, sex, race/ethnicity, baseline heart health status, baseline renal function, or other factors.

Conditions:

🦠 Type 2 Diabetes Mellitus 🦠 Cardiovascular Diseases

🗓️ Study Start (Actual) 1 July 2021

🗓️ Primary Completion (Estimated) 30 June 2024

✅ Study Completion (Estimated) 30 August 2025

👥 Enrollment (Estimated) 270000

🔬 Study Type OBSERVATIONAL

📊 Phase N/A

Locations:

📍 Oakland, California, United States

📍 Pasadena, California, United States

📍 Honolulu, Hawaii, United States

📍 Detroit, Michigan, United States

📍 Bloomington, Minnesota, United States

📍 Danville, Pennsylvania, United States

📋 Eligibility Criteria

Description

* Dispensing of either of the set of drugs being compared
* No prior dispensing of any of the drugs compared
* Evidence of Type 2 Diabetes Mellitus diagnosis
* Age 18-85
* Not currently pregnant
* No evidence of dementia or short-term life expectancy from prior cancer diagnoses
* History of ≥2 years of continuous health plan membership
* ≥1 A1c test in the past 18 months

Ages Eligible for Study: 18 Years to 85 Years (ADULT, OLDER_ADULT)

Sexes Eligible for Study: ALL

Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted 14 September 2021
First Submitted that Met QC Criteria 1 October 2021
First Posted 11 October 2021

Study Record Updates