Inclusion Criteria:

• 1. Healthy, overweight or obese individuals.

Exclusion Criteria:

• 1. Participants must have a body mass index (BMI) greater than or equal to 27 kilograms per meter squared.
• 2. No history of drug or alcohol dependency. Must be current non-smokers, and are required to have a history of less than 5 pack years of smoking.
• 3. No history of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study. In addition to this, individuals must not have traveled across more than 1 time zone during the 3 months prior to the study.
• 4. Chronobiologic and sleep disorders.
• 5. Diseases of the cardiovascular system.
• 6. Hypertension. Individuals will be allowed to be normotensive (resting systolic blood pressure of \<140/90 mmHg, measured on more than one occasion) or uncomplicated stage 1 hypertension (systolic BP between 140 and 159 mmHg or a diastolic BP between 90 and 99 mmHg).
• 7. Disorders of the respiratory system.
• 8. Pre-diabetes/Diabetes. For participants who have a fasting blood glucose level that is greater than or equal to 100 mg/dL, the investigators will measure hemoglobin A1c to exclude for diabetes (HbA1c\>5.7%).
• 9. Disorders of the kidney and urinary tract.
• 10. Infectious diseases.
• 11. Disorders of the gastrointestinal system.
• 12. Disorders of the immune system.
• 13. Disorders of the hematopoietic system.
• 14. Neoplastic diseases.
• 15. Endocrine and metabolic diseases.
• 16. Neurologic disorders.
• 17. Must not be participating in another research study that would influence their safe participation in the study.