Description
Inclusion Criteria:
- * Male or female child/adolescent up to 18 years of age with CKD
- * estimated glomerular filtration rate (eGFR) of 30 to 90 ml/min/1.73 m2
- * diagnosed with hypertension and on a stable dose of anti-hypertensive medication(s) for at least 3 months
- * Non-dipping identified on ABPM
Exclusion Criteria:
- * history of organ transplantation, oncological disease, or dialysis
- * inability to complete 24-hour ABPM or 24-hour urine collection
- * Children less than 6 years of age will be excluded, as they often are unable to complete a successful ABPM study (≥ 40 readings, with 1 reading per hour of sleep)
- * Currently on diuretic medications.
Ages Eligible for Study:
6 Years to 18 Years (CHILD, ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No