Description
Inclusion Criteria:
- * Between 9 and 25 years of age at time of study enrollment
- * Currently receiving care for cancer at St. Jude
- * Diagnosed with severe sepsis according to consensus criteria
Exclusion Criteria:
- * History of allogeneic hematopoietic cell transplantation or CAR-T cell therapy
- * Participant has been diagnosed with clinically significant left ventricular dysfunction (EF \< 55%) prior to the onset of sepsis
- * Participant has any condition that would, in the opinion of the investigator, place the subject at an unacceptable risk of injury or render the subject unable to meet the requirements of the protocol. Participant is pregnant.
- * Estimated glomerular filtration rate \< 45 ml/minute/1.73m2
- * Does not meet MRI safety screening criteria.
Ages Eligible for Study:
9 Years to 25 Years (CHILD, ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No