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Cardiovascular and Neurovascular Regulation in GWI
Brain blood flow regulation and autonomic dysfunction will be measured in Veterans with and without Gulf War Illness who served in the Gulf War between 1990 and 1992.
Conditions:
🦠 Brain Blood Flow 🦠 Neurovascular Control
🗓️ Study Start (Actual) 16 May 2023
🗓️ Primary Completion (Estimated) September 2024
✅ Study Completion (Estimated) September 2024
👥 Enrollment (Estimated) 70
🔬 Study Type OBSERVATIONAL
📊 Phase N/A
Locations:
📍 Madison, Wisconsin, United States

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Deployed to the Persian Gulf between 1990-1992
    • * Body mass \<300 lbs
    • * Diagnosis of Gulf War Illness based on CMI/CDC and Kansas definitions or No diagnosis of Gulf War Illness

    Exclusion Criteria:

    • * Current or lifetime evidence of: Type II diabetes, neurological disease, cancer treatment, rheumatoid arthritis, lupus, bipolar disorder, psychotic disorders, or mood disorders with psychotic features
    • * Current illicit substance use or partial remission for less than 1 year
    • * Taking multiple sedatives or anticonvulsant medications
    • * Currently pregnant
    • * Absolute contraindications to exercise testing
    • * Contraindications to MRI
    • * Other significant medical conditions at investigator's discretion
Ages Eligible for Study: 45 Years to 68 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 6 October 2020
  • First Submitted that Met QC Criteria 6 October 2020
  • First Posted 14 October 2020

Study Record Updates

  • Last Update Submitted that Met QC Criteria 22 September 2023
  • Last Update Posted 26 September 2023
  • Last Verified September 2023
I'm interested ...!!