Description
Inclusion Criteria:
- Inclusion Criteria (control participants):
- * Be 45-90 years of age
- * Have adequate language and neurocognitive function to participate in training and testing
- * Be medically stable to participate in the study
- * Be English speaking
- Inclusion Criteria (participants with stroke):
- * Be 45-90 years of age
- * Clinically defined, unilateral, hemiparetic stroke with radiologic exclusion of other possible diagnosis
- * Stroke onset at least 6 months before enrollment
- * Subcortical stroke (ex: internal capsule, deep white matter of posterior frontal lobe)
- * Present with mild to moderate arm dysfunction
- * Be medically stable to participate in the study
- * Be English speaking
Exclusion Criteria:
- (for both groups)
- * Unable to give informed consent
- * Have a serious complicating medical illness that would preclude participation
- * Contractures or orthopedic problems limiting range of joint motion in the potential study arm or other impairments that would interfere with the study activities
- * Visual loss such that the subject would not be able to see the test patterns on the robot computer monitor
- * Unable to comply with requirements of the study
- * Enrollment in another greater-than-minimal risk study
- * Presence of medical condition or implant that prevents safe administration of TMS or MRI
- * Pregnancy
Ages Eligible for Study:
45 Years to 90 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Yes