Description
Inclusion Criteria:
- * Adults 18-70 years of age
- * Chronic SCI for \> 1 year, at or below C-3 to T-12
- * Incomplete SCI based on residual sensory or motor function below the level of the injury, or injury classification of B, C, D at initial screening, according to the American Spinal Injury Association Impairment Classification, and the International Standards for the Neurological Classification of SCI
- * Medically stable with physician clearance
- * SCI due to non-progressive etiology
- * 20% impairment in maximal inspiratory or expiratory pressure generation, relative to normative values
Exclusion Criteria:
- * Current diagnosis of an additional neurologic condition such as Multiple Sclerosis, Parkinson disease, stroke, or brain injury
- * Severe illness or infection, including non-healing decubitus ulcers, untreated bladder or urinary tract infections, cardiovascular disease, lung disease, active heterotopic ossification, or uncontrolled hypertension
- * Severe neuropathic pain
- * Known pregnancy
- * Severe recurrent autonomic dysreflexia
- Exclusion for involvement in TMS - History of seizure disorder, uncontrolled migraines, presence of cardiac pacemaker, metal implants in skull, medications that lower seizure threshold.
Ages Eligible for Study:
18 Years to 70 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No