Inclusion Criteria:

• * Age of Subjects: Patients ≥ 18 years of age.
• * Gender of Subjects: Both males and females will be invited to participate.
• * Subjects with diabetes (A1C level 6.5 or higher) or Fasting Plasma Glucose (blood sugar level) 126 mg/dL (≥7.0 mmol/L)
• * Subjects must be willing and are able to comply with clinic visit, understand the study-related procedures/provisions, and provide signed informed consent.
• * asymptomatic patients with DR.

Exclusion Criteria:

• * Subject has retinal degenerations and retinal vascular diseases such as age-related macular degeneration or having undergone prior retinal surgery.
• * History of ocular injections,
• * Subject has persistent visual impairment in any eye;
• * History of macular edema or retinal vascular (vein or artery) occlusion;
• * laser treatment of the retina, or intraocular surgery other than cataract surgery without complications;
• * Subject is currently enrolled in an interventional study of an investigational device or drug;
• * Subject has ungradable clinical reference standard photographs (i.e., not gradable quality image). If the patient image is not gradable automatically, we will suggest the patient to refer the ophthalmologist.