Description
Inclusion Criteria:
- * Established diagnosis of COVID-19 requiring admission to the hospital for treatment of COVID-19 infection
- * Age 3 years - 21 years of age
Exclusion Criteria:
- * Severe hepatic dysfunction: ALT\> 6 x Upper limit of normal
- * Renal dysfunction: Creatinine \> 1.5 x upper limit of normal or on dialysis
- * Acute Stroke
- * Pregnancy
- * Allergy to arginine
- * Past history of severe cardiac disease or significant cardiac surgery \[minor procedures like ventricular septal defect (VSD) repair are not an exclusion\]
- * History of significant pulmonary disease \[Cystic Fibrosis, sickle cell disease (SCD)\]
- * History of organ transplant
- * History of metabolic or mitochondrial disease (including Diabetes)
- * History of severe neurocognitive delays (severe cerebral palsy, anoxic brain injury)
- * History of ventriculoperitoneal (VP) shunt or hydrocephalus
- * PI discretion that the patient is not an ideal candidate for the study
- * History of HIV of immune compromise
Ages Eligible for Study:
3 Years to 21 Years (CHILD, ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No