Description
Inclusion Criteria:
- * Age greater than or equal to 18 years old.
- * At least three months status post heart transplantation.
Exclusion Criteria:
- * Biopsy proven acute rejection episode in the past 3 months.
- * Patients with symptoms or signs of acute myocardial ischemia or recent acute coronary syndrome in the past 3 months.
- * Uncontrolled obstructive ventilatory disease including asthma and COPD.
- * History of generalized tonic-clonic seizures.
- * Second or third degree AV nodal block.
- * Sinus node dysfunction.
- * Contraindications to MRI including cardiovascular implantable electronic devices.
- * Renal dysfunction with an estimated GFR less than 30 mL/min/1.73m2.
- * Prior adverse reaction to either regadenoson or gadolinium contrast. Prior adverse reaction to adenosine or dipyridamole will be assessed on a case-by-case basis.
- * Systolic blood pressure greater than 180 or less than 85 mmHg.
- * Diastolic blood pressure greater than 120 or less than 40 mmHg.
- * Resting heart rate greater than 120 or less than 45 beats per minute. - Severe claustrophobia.
Ages Eligible for Study:
18 Years to N/A (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
No