Description
Inclusion Criteria:
- * Have a body mass index within the range of 18.0 to 32 kilograms per square meter (kg/mΒ²)
- * Males who agree to follow contraceptive requirements and women of not childbearing potential
- * Have body weight greater than or equal to (\>=) 50 Kilograms at screening.
- * Must have a negative Interferon-Gamma Release Assays (IGRA) testing at screening
- * Must have been stopped all the prescribed medication at least 14 days prior to admission to the clinical site
- * Ability and willingness to abstain from alcohol, caffeine, and methylxanthine-containing beverages or food 2 days prior to admission to the clinical site
- * Abstain from any strenuous physical exercise from 4 days prior to admission and during confinement at the clinical site
Exclusion Criteria:
- * Have a history of relevant drug and/or food allergies, or sensitivity to medications used in the current study
- * Females participants who are currently breastfeeding
- * Have History of alcohol abuse or drug addiction
- * Unable to abstain from tobacco products within the 2 days prior to admission and during confinement at the clinical site
- * Have Positive screen for hepatitis B surface antigen, hepatitis C virus (HCV) antibodies, or human immunodeficiency virus (HIV) 1 and 2 antibodies
- * Consumption of any nutrients known to modulate CYP450 enzymes activity
- * Are immunocompromised
- * Have received live vaccine(s) (including attenuated live vaccines) or Bacillus Calmette-GuΓ©rin within 28 days of screening or intend to receive them during the study
- * Have had any malignancy within the past 5 years
Ages Eligible for Study:
18 Years to 55 Years (ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Yes