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A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis
The main purpose of this study is to determine the efficacy and safety of LY3972406 in adult participants with moderate-to-severe plaque psoriasis.
Conditions:
🦠 Plaque Psoriasis
🗓️ Study Start (Actual) 6 December 2023
🗓️ Primary Completion (Estimated) April 2025
✅ Study Completion (Estimated) July 2025
👥 Enrollment (Estimated) 75
🔬 Study Type INTERVENTIONAL
📊 Phase PHASE2
Locations:
📍 Los Angeles, California, United States
📍 Santa Monica, California, United States
📍 Coral Gables, Florida, United States
📍 Winter Park, Florida, United States
📍 East Windsor, New Jersey, United States
📍 Hackensack, New Jersey, United States
📍 Kenilworth, New Jersey, United States
📍 Winston-Salem, North Carolina, United States
📍 Columbus, Ohio, United States
📍 Camp Hill, Pennsylvania, United States
📍 Houston, Texas, United States
📍 Houston, Texas, United States
More locations available...

📋 Eligibility Criteria

Description

    Inclusion Criteria:

    • * Have moderate-to-severe chronic plaque psoriasis for at least 6 months prior to baseline
    • * Have venous access sufficient to allow for blood sampling
    • * Are able to swallow oral medication
    • * Agree to skin biopsies

    Exclusion Criteria:

    • * Have any other skin conditions, excluding plaque psoriasis
    • * Have a current or recent acute, active infection
    • * Have manifestations of other autoimmune diseases, such as systemic lupus erythematosus.
    • * Are lactating or breastfeeding women
Ages Eligible for Study: 18 Years to 75 Years (ADULT, OLDER_ADULT)
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

  • First Submitted 11 December 2023
  • First Submitted that Met QC Criteria 11 December 2023
  • First Posted 20 December 2023

Study Record Updates

  • Last Update Submitted that Met QC Criteria 17 June 2024
  • Last Update Posted 18 June 2024
  • Last Verified June 2024
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