A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

RECRUITING

I'm interested ...!!

Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.

Conditions:

🦠 Gastroesophageal Reflux 🦠 Regurgitation 🦠 Heartburn

🗓️ Study Start (Actual) 17 November 2023

🗓️ Primary Completion (Estimated) 31 December 2024

✅ Study Completion (Estimated) 31 December 2024

👥 Enrollment (Estimated) 50

🔬 Study Type INTERVENTIONAL

📊 Phase NA

Locations:

📍 Jacksonville, Florida, United States

📋 Eligibility Criteria

Description

Inclusion Criteria:

* Predominant symptoms of gastroesophageal reflux disease including heartburn, regurgitation
* Subjects must be able to give appropriate informed consent

Exclusion Criteria:

* Prior diagnosis of SIBO
* Use of PPIs or H2R-anatagonstists in the prior 3 months
* Major concomitant illness (renal, hepatic, rheumatologic or cardiovascular disease, or malignancy)
* Antibiotic therapy within one month
* Prior gastrointestinal surgery including esophageal, gastric, and small or large bowel surgery
* Previously diagnosed irritable bowel syndrome or inflammatory bowel disease
* Individuals who are pregnant or breast feeding
* Patients with plans to become pregnant
* Inability to take PPIs, including allergy/sensitivity

Ages Eligible for Study: 18 Years to N/A (ADULT, OLDER_ADULT)

Sexes Eligible for Study: ALL

Accepts Healthy Volunteers: No

🗓️ Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted 27 July 2023
First Submitted that Met QC Criteria 27 July 2023
First Posted 4 August 2023

Study Record Updates

Last Update Submitted that Met QC Criteria 11 June 2024
Last Update Posted 12 June 2024
Last Verified June 2024