What does 'adjuvant setting' mean in cancer clinical trials?
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Hello OncologyInsights, great question! In oncology trials, adjuvant setting refers to the use of additional treatments after the primary treatment (like surgery or radiation) to reduce the risk of cancer recurrence. These trials aim to test the efficacy and safety of these adjuvant therapies in improving patient outcomes.
For instance, in breast cancer treatment, patients might undergo surgery to remove the tumor, followed by adjuvant chemotherapy or hormone therapy to destroy any remaining cancer cells. In clinical trials, researchers compare the outcomes of different adjuvant therapies to find the most effective treatment approach.
It's important to note that adjuvant therapies are not the same as neoadjuvant therapies, which are given before the primary treatment to shrink the tumor. Both adjuvant and neoadjuvant settings are crucial in oncology trials, helping researchers develop better treatment strategies and improve patient survival.
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