Community Questions & Discussions

Thoughts on the Upadacitinib Clinical Trial for Lupus Patients

I'm curious to hear your thoughts on the study titled 'Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Patients With Moderate to Severe Lupus'. This phase III trial aims to evaluate the safety and efficacy of Upadacitinib, an oral JAK1 inhibitor, in pati...

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Thoughts on the 'Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE' Study?

I recently came across the 'Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE' study, which looks at a new treatment approach for lupus patients. The study focuses on how anifrolumab affects the immune response to vaccines in people with systemic lupus erythematosus (SLE). As someone ...

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Thoughts on the new BIIB059 (Litifilimab) clinical trial for SCLE and CCLE lupus patients?

The recent 'A Study to Assess the Effectiveness and Safety of BIIB059 (Litifilimab) in Patients With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Thera...

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Thoughts on a Lupus Communication and Medication Adherence Study

I recently came across a study titled 'Intervention to Improve Communication and Medication Adherence in Lupus' and was curious about the goals and outcomes. Have any of you heard about or participated in this study? What are your thoughts on its potential impact for those with lupus or other autoim...

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Sharing thoughts on the 'Study Medicine' trial for active Cutaneous Lupus or Systemic Lupus Erythematosus

Have you heard about the new clinical trial titled 'A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms?' It aims to evaluate the safety and effectiveness of an investigational drug for adults with Cutaneous Lupus Erythematosus (CLE) or Systemi...

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Sharing Thoughts on a Recent Lupus Clinical Trial: 'A Study in Patients With Mild-to-moderate Lupus'

Have any of you heard about the recent clinical trial for patients with mild-to-moderate lupus? The study explores new treatment options, and I'm curious to know what the community thinks about its goals and potential outcomes. It's exciting to see more research being done for autoimmune diseases li...

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Thoughts on the new Obinutuzumab study for adolescents with lupus nephritis?

I recently came across the 'A Study to Evaluate the Effectiveness, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Patients' study. What are your thoughts on this approach for addressing lupus ...

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Exploring the Potential of CD19 CAR T-Cell Therapy in Refractory Lupus Nephritis

I came across a recent study titled 'KYSA-1: Study on Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis'. This trial aims to evaluate the safety and efficacy of CD19 CAR T-cell therapy in treating patients with lupus nephritis who have not r...

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Thoughts on the KYSA-1 Study Using CAR T-Cell Therapy for Refractory Lupus Nephritis?

I recently came across the 'KYSA-1: Study on Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis' study and was intrigued by its approach to addressing lupus challenges. For those unfamiliar, this study investigates the safety and efficacy of ...

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Thoughts on the Obinutuzumab Clinical Trial for Lupus Patients?

I recently came across the 'A Study to Evaluate the Effectiveness and Safety of Obinutuzumab in Patients With Lupus' trial and was wondering how the community feels about this approach. The study aims to evaluate the effectiveness of Obinutuzumab, an FDA-approved treatment for certain types of cance...

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Discussing the Goals and Outcomes of a Pediatric Rheumatologic Condition Study

I recently came across a study titled 'Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions', and it got me thinking about the goals and outcomes of clinical trials for autoimmune diseases like lupus. This study focuses on developing new endpoints to evaluate treatments for pe...

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Thoughts on a New Educational Tool for Lupus Patients Considering Immune Checkpoint Inhibitors?

I recently came across a clinical trial that's testing an educational tool for patients with melanoma and pre-existing autoimmune diseases (like lupus) who are candidates for immune checkpoint inhibitors. The goal is to help these patients better understand the risks and benefits of this treatment o...

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Thoughts on the 'FT819 in Moderate to Severe Active Lupus' Clinical Trial Approach?

I recently came across the 'FT819 in Moderate to Severe Active Lupus' clinical trial and was wondering how the community feels about this approach to addressing lupus challenges? The trial focuses on a novel anti-CD40L antibody, aiming to selectively deplete autoreactive B cells. What are your thoug...

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Thoughts on the Felzartamab Study for Lupus Nephritis?

I recently came across the 'Study on Felzartamab in Patients With Lupus Nephritis' and was wondering how the community feels about this approach to addressing lupus challenges. The trial aims to evaluate the safety and efficacy of Felzartamab, an investigational therapy, in patients with active lupu...

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Thoughts on the Maternal Autoimmune Disease Research Alliance (MADRA) Registry for Lupus?

I recently came across the 'Maternal Autoimmune Disease Research Alliance (MADRA) Registry' study that aims to address lupus challenges. This approach focuses on collecting data from pregnant women with lupus and other autoimmune diseases to better understand the impact of these conditions on pregna...

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