Clinical Trials

RECRUITING
T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer
This study will evaluate whether simvastatin reduces intraprostatic immunosuppressive microenvironment through YAP-mediated T-reg dysfunction, and inc...
Conditions:
Prostate Cancer
Locations:
📍 Charleston, South Carolina, United States
RECRUITING
Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer
This phase II trial studies how well using circulating tumor deoxyribonucleic acid (DNA) to guide lower dose radiation therapy works in treating patie...
Conditions:
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Oropharyngeal Squamous Cell Carcinoma
Locations:
📍 Columbus, Ohio, United States
RECRUITING
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma
Background: Pheochromocytoma and paraganglioma are rare tumors. They usually form inside and near the adrenal gland or in the neck region. Not all th...
Conditions:
Pheochromocytoma Paraganglioma Neuroendocrine Tumors Neuroendocrine Neoplasms
Locations:
📍 San Francisco, California, United States
📍 Bethesda, Maryland, United States
📍 Philadelphia, Pennsylvania, United States
RECRUITING
Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone
This phase I trial investigates the safety of testosterone replacement therapy around the time of major urologic surgery (perioperative) in order to i...
Conditions:
Hypogonadism Malignant Urinary System Neoplasm Urinary System Disorder Urinary System Neoplasm
Locations:
📍 Atlanta, Georgia, United States
RECRUITING
A Study of Sargramostim Plus Pembrolizumab With or Without Pemetrexed in Patients With Advance Non-small Cell Lung Cancer After Completion of Chemoimmunotherapy
Metastatic lung cancer is the leading cause of cancer mortality worldwide with a 5-year survival of less than 5%. With the approval of programmed cell...
Conditions:
Advanced Lung Non-Small Cell Carcinoma Non-Small Cell Carcinoma of Lung, TNM Stage 4
Locations:
📍 Boston, Massachusetts, United States
RECRUITING
LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)
This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies f...
Conditions:
Non-small Cell Lung Cancer Oligoprogressive Small-cell Lung Cancer
Locations:
📍 Sacramento, California, United States
RECRUITING
Behavioral Parenting Skills As A Novel Target for Improving Pediatric Medication Adherence
This study observes behavioral parenting skills to see whether it could be a novel target for improving pediatric medication adherence. This study may...
Conditions:
Acute Lymphoblastic Leukemia
Locations:
📍 Buffalo, New York, United States
RECRUITING
Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer
This phase Ib/II trial studies the side effects and best dose of ribociclib, tucatinib, and trastuzumab for the treatment of HER2 positive breast canc...
Conditions:
Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage IIA Breast Cancer AJCC v8 Anatomic Stage IIB Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8
16 more conditions available...
Locations:
📍 Los Angeles, California, United States
RECRUITING
Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients
This study aims to determine if web-based eHealth delivery of pre-test and/or post-test counseling in cancer patients and/or those at risk for cancer ...
Conditions:
Cancer
Locations:
📍 Philadelphia, Pennsylvania, United States
RECRUITING
Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations
This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metast...
Conditions:
Bile Duct Adenocarcinoma Fanconi Anemia Complementation Group Gene Mutation Metastatic Bile Duct Carcinoma PTEN Gene Deletion
Locations:
📍 Scottsdale, Arizona, United States
📍 Jacksonville, Florida, United States
📍 Boston, Massachusetts, United States
📍 Rochester, Minnesota, United States
2 more locations available...
RECRUITING
Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)
Background: Pancreatic cancer is one of the most lethal types of cancer. ASCP is a highly aggressive type of pancreatic cancer. It is very rare. Rese...
Conditions:
Adenosquamous Carcinoma of the Pancreas
Locations:
📍 Bethesda, Maryland, United States
RECRUITING
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers
This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-...
Conditions:
Bladder Carcinoma Cervical Carcinoma Cholangiocarcinoma Hematopoietic and Lymphoid Cell Neoplasm
12 more conditions available...
Locations:
📍 Los Angeles, California, United States
RECRUITING
Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)
This is a phase III, single-arm, multicenter, international study to assess the efficacy and safety of ONCOFID-P-B following intravesical instillation...
Conditions:
Bladder Carcinoma in Situ (CIS)
Locations:
📍 Gilbert, Arizona, United States
📍 New Orleans, Louisiana, United States
📍 Baltimore, Maryland, United States
📍 Minneapolis, Minnesota, United States
30 more locations available...
RECRUITING
Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
This study is to evaluate the disease control rate and time to progression of the sequential combination of oxaliplatin with an alternative anti-metab...
Conditions:
Colon Cancer Rectal Cancer
Locations:
📍 Elizabeth, New Jersey, United States
📍 Jersey City, New Jersey, United States
📍 Lakewood, New Jersey, United States
📍 Livingston, New Jersey, United States
5 more locations available...
RECRUITING
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
This study assesses how blood cell growth patterns (clonal hematopoiesis), relates to heart health or cardiovascular disease (CVD) after treatment in ...
Conditions:
Cardiovascular Disorder Clonal Hematopoiesis Hodgkin Lymphoma
Locations:
📍 Tampa, Florida, United States
📍 Ann Arbor, Michigan, United States
📍 Saint Louis, Missouri, United States
📍 Hackensack, New Jersey, United States
8 more locations available...

Total Trials: 91 - 105 of 6772