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Clinical Trials
RECRUITING
Supporting Tailored And Responsive PrEP in Rural North Carolina
This project consists of two phases to be completed over five years. Phase 1 (Aims 1 and 2) will be completed during Years 1-3 (R61). The Phase 1 stud...
Conditions:
HIV Pre-Exposure Prophylaxis
Locations:
📍
Chapel Hill, North Carolina, United States
RECRUITING
Host Response to Infection and Treatment in Filarial Diseases
This study will evaluate and treat patients with filarial infections to explore in depth the immunology of the disease, including susceptibility to in...
Conditions:
Filariasis
Helminthiasis
Parasitic Infection
Mansonelliasis
1 more condition available...
Locations:
📍
Bethesda, Maryland, United States
RECRUITING
Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD
This study aims to test a remotely delivered IOP program ("SmartIOP") for OUD patients who are hospitalized for serious injection-related infections. ...
Conditions:
Opioid Use Disorder
Serious Bacterial Infections
Locations:
📍
Boston, Massachusetts, United States
RECRUITING
Epigenetic Regulation of Altered T-cell Immunity in Sarcoidosis
Sarcoidosis is a multi-system granulomatous disorder that is triggered and influenced by gene-environment interactions. Although sarcoidosis predomina...
Conditions:
Sarcoidosis
Sarcoidosis, Pulmonary
Locations:
📍
San Francisco, California, United States
RECRUITING
Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts
This is a Phase I dose-escalation study to evaluate the safety of norovirus -specific T-cell (NST) therapy for chronic norovirus infection in particip...
Conditions:
Viral Infection
Hematopoietic Stem Cell Transplantation (HSCT)
Primary Immunodeficiency Disorders (PID)
Locations:
📍
Washington, District of Columbia, United States
📍
Bethesda, Maryland, United States
RECRUITING
A Phase 2 Study to Evaluate the Safety, Tolerability, and Immunogenicity of AFX3772 Vaccine in Healthy Infants
This is a Phase 2 clinical study to support the use of AFX3772 in healthy infants for the prevention of pneumococcal disease. The purpose of this stud...
Conditions:
Pneumonia, Bacterial
Pneumococcal Infections
Pneumonia, Pneumococcal
Locations:
📍
Phoenix, Arizona, United States
📍
Tucson, Arizona, United States
📍
Jonesboro, Arkansas, United States
📍
Los Angeles, California, United States
25 more locations available...
RECRUITING
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and el...
Conditions:
COVID-19
Locations:
📍
Birmingham, Alabama, United States
📍
Phoenix, Arizona, United States
📍
Little Rock, Arkansas, United States
📍
Los Angeles, California, United States
102 more locations available...
RECRUITING
Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections
This will be a single-center randomized control trial comparing the efficacy of two different formulations of Chlorhexidine surgical skin preparation ...
Conditions:
Surgical Site Infection
Cesarean Section; Infection
Locations:
📍
Pittsburgh, Pennsylvania, United States
RECRUITING
Respiratory Virus Sampling and Repository
Background: Respiratory viruses, like the flu or COVID-19, cause significant illness and death worldwide. Researchers want to collect samples from pe...
Conditions:
Influenza
COVID-19
Locations:
📍
Bethesda, Maryland, United States
📍
Bethesda, Maryland, United States
RECRUITING
Qualitative Assessment of the Impact of TTNS on QOL and Participation
This study through the use of semi-structured interviews or focus groups will explore the lived experience with Transcutaneous Tibial Nerve Stimulatio...
Conditions:
Neurogenic Bladder
Urinary Retention
Urinary Tract Infections
Spinal Cord Injuries
Locations:
📍
Washington, District of Columbia, United States
RECRUITING
8.4% Sodium Bicarbonate Locks in Intestinal Failure
We plan to include children with intestinal failure, a condition where the gut is not functioning properly, leading these children to need central ven...
Conditions:
Intestinal Failure
CRBSI - Catheter Related Bloodstream Infection
Locations:
📍
Iowa City, Iowa, United States
RECRUITING
T CELL THERAPY OPPOSING NOVEL COVID-19 INFECTION IN IMMUNOCOMPROMISED PATIENTS
This is an open label, phase I dose-escalation study to evaluate the safety of coronavirus-specific T cell (CST) therapy for prevention of SARS-CoV-2 ...
Conditions:
SARS-CoV-2 Infection
Locations:
📍
Washington, District of Columbia, United States
📍
Baltimore, Maryland, United States
NOT_YET_RECRUITING
Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
The body has different ways of fighting infection and disease. No single way seems perfect for fighting cancers. This research study combines two diff...
Conditions:
Hepatoblastoma
Hepatocellular Carcinoma
Wilms Tumor
Malignant Rhabdoid Tumor
4 more conditions available...
Locations:
📍
Houston, Texas, United States
RECRUITING
Changes in Immunologic Parameters Following the Addition of Fostemsavir in Virologically Suppressed Immunologic Non-responders Living With HIV-the RECOVER Study
The RECOVER study is a self-controlled case series to evaluate whether the addition of Fostemsavir (Rukobia) to a stable HIV regimen in virologically ...
Conditions:
HIV-1-infection
Locations:
📍
Orlando, Florida, United States
RECRUITING
Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19
The primary objective of this study is to determine, in unblinded samples, whether artificial intelligence can classify specific blood RNA from patien...
Conditions:
Long COVID
Locations:
📍
Brentwood, Tennessee, United States
📍
Brentwood, Tennessee, United States
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Total Trials:
76 - 90 of 1083