Clinical Trials

RECRUITING
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
This treatment trial assesss the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose ...
Conditions:
High Risk Pregnancy Pregnancy Complications Antiphospholipid Syndrome in Pregnancy Lupus Anticoagulant Disorder
Locations:
📍 New York, New York, United States
📍 Salt Lake City, Utah, United States
📍 Toronto, Ontario, Canada
RECRUITING
Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
Social determinants of health (SDoH), defined by the World Health Organization as "the conditions in which people are born, grow, work, live and age a...
Conditions:
Rheumatoid Arthritis Palindromic Arthritis Juvenile Rheumatoid Arthritis Ankylosing Spondylitis
10 more conditions available...
Locations:
📍 Boston, Massachusetts, United States
RECRUITING
The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Lupus (SLE) - IFN-CVD
Background: People with systemic lupus erythematosus (SLE) are at risk of developing complications in their blood vessels. This can increase the risk...
Conditions:
Systemic Lupus Erythematosus Cardiovascular Disease Premature Atherosclerosis
Locations:
📍 Bethesda, Maryland, United States
RECRUITING
KYSA-1: Study on Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
A Study of Anti-CD19 Chimeric Antigen Receptor T Cell Therapy for Subjects With Refractory Lupus Nephritis
Conditions:
Lupus Nephritis Lupus Nephritis - World Health Organization (WHO) Class III Lupus Nephritis - WHO Class IV
Locations:
📍 Palo Alto, California, United States
📍 Denver, Colorado, United States
📍 Worcester, Massachusetts, United States
📍 Great Neck, New York, United States
2 more locations available...
RECRUITING
Study on Felzartamab in Patients With Lupus Nephritis
The goal of this clinical trial is to assess the safety and tolerability of felzartamab plus standard of care in patients with refractory Lupus Nephri...
Conditions:
Lupus Nephritis
Locations:
📍 La Jolla, California, United States
📍 Stanford, California, United States
📍 Columbus, Georgia, United States
📍 Lawrenceville, Georgia, United States
12 more locations available...
RECRUITING
Phase 2 Placebo-Controlled Study to Assess the Safety and Effectiveness of ESK-001 in Active Lupus
The purpose of this study is to assess the clinical efficacy, safety, PK, and PD of multiple dose levels of ESK-001 compared with placebo in adult pat...
Conditions:
SLE
Locations:
📍 Anniston, Alabama, United States
📍 Hoover, Alabama, United States
📍 Los Alamitos, California, United States
📍 Upland, California, United States
143 more locations available...
RECRUITING
Treatment of Lupus (SLE) With N-acetylcysteine
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease which often has debilitating and potentially life-threatening consequences. The c...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Los Angeles, California, United States
📍 New Haven, Connecticut, United States
📍 New York, New York, United States
📍 Syracuse, New York, United States
1 more location available...
RECRUITING
Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome
Antiphospholipid antibody syndrome (APS) is characterized by the presence of antiphospholipid antibodies, which are proteins in the blood that interfe...
Conditions:
Antiphospholipid Syndrome
Locations:
📍 Durham, North Carolina, United States
RECRUITING
Duke Lupus Registry
Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can...
Conditions:
Systemic Lupus Erythematosus Cutaneous Lupus
Locations:
📍 Durham, North Carolina, United States
RECRUITING
Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus
The primary purpose of this study is to assess the potential effectiveness of 24 weeks of MMF within previously discovered immunologically defined sub...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Los Angeles, California, United States
📍 New Haven, Connecticut, United States
📍 Atlanta, Georgia, United States
📍 Atlanta, Georgia, United States
7 more locations available...
RECRUITING
Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)
This study is being done to find out if a non-invasive Magnetic Resonance Imaging (MRI) examination of the kidneys may be helpful for diagnosing lupus...
Conditions:
Lupus Nephritis Lupus Erythematosus, Systemic Lupus SLE
3 more conditions available...
Locations:
📍 Baltimore, Maryland, United States
RECRUITING
Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study of ALXN2050 (120 and 180 milligrams \[mg\]) in addition to backgrou...
Conditions:
Lupus Nephritis Immunoglobulin A Nephropathy IgAN LN
Locations:
📍 Huntsville, Alabama, United States
📍 Tucson, Arizona, United States
📍 La Jolla, California, United States
📍 Loma Linda, California, United States
121 more locations available...
RECRUITING
Characteristics and Disease Progression of Mixed Connective Tissue Disease and Lupus
Systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) are long-term autoimmune diseases in which the immune system attacks par...
Conditions:
Mixed Connective Tissue Disease (MCTD) Systemic Lupus Erythematosus (SLE)
Locations:
📍 Miami, Florida, United States
RECRUITING
Phase 2 Trial of Mesenchymal Stem Cells in Lupus (MiSLE)
The purpose of this study is to assess the efficacy and safety of mesenchymal stem cells (MSCs) obtained from umbilical cords for the treatment of adu...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Los Angeles, California, United States
📍 San Diego, California, United States
📍 Atlanta, Georgia, United States
📍 Chicago, Illinois, United States
5 more locations available...
RECRUITING
A Study to Evaluate the Effectiveness and Safety of Obinutuzumab in Patients With Lupus
This parallel-group, double-blind, placebo-controlled study will assess the efficacy and safety of obinutuzumab versus placebo in patients with active...
Conditions:
Systemic Lupus Erythematosus
Locations:
📍 Anniston, Alabama, United States
📍 Birmingham, Alabama, United States
📍 Searcy, Arkansas, United States
📍 Fullerton, California, United States
101 more locations available...

Total Trials: 16 - 30 of 110